5-(1-phenyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)-N-p-tolyl-1,3,4-oxadiazol-2-amine

Base Information

Chemical Name:5-(1-phenyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)-N-p-tolyl-1,3,4-oxadiazol-2-amine
CAS No.:1620993-54-5
Molecular Formula:C₂₃H₁₈N₆O
Molecular Weight:394.436
Hs Code.:

Synonyms:5-(1-phenyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)-N-p-tolyl-1,3,4-oxadiazol-2-amine

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Chemical Property of 5-(1-phenyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)-N-p-tolyl-1,3,4-oxadiazol-2-amine

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Technology Process of 5-(1-phenyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)-N-p-tolyl-1,3,4-oxadiazol-2-amine

There total 5 articles about 5-(1-phenyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)-N-p-tolyl-1,3,4-oxadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 1620992-57-5
2-(1-phenyl-5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl)-N-p-tolylhydrazine-carbothioamide

: 1620993-54-5
5-(1-phenyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)-N-p-tolyl-1,3,4-oxadiazol-2-amine

Guidance literature:: With mercury(II) oxide; In ethanol; for 2h; Reflux;
DOI:10.2174/15734064113096660044

Reference yield:

: 1620993-50-1
1-phenyl-5-(pyridin-4-yl)-1H-pyrazole-3-carbohydrazide

: 1620993-54-5
5-(1-phenyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)-N-p-tolyl-1,3,4-oxadiazol-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / Reflux

2: mercury(II) oxide / ethanol / 2 h / Reflux

With mercury(II) oxide; In methanol; ethanol;
DOI:10.2174/15734064113096660044

Reference yield:

: 1122-54-9
methyl (4-pyridyl) ketone

: 1620993-54-5
5-(1-phenyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)-N-p-tolyl-1,3,4-oxadiazol-2-amine

Guidance literature:: Multi-step reaction with 5 steps

1: sodium methylate; sodium / methanol; diethyl ether / 1 h / Cooling with ice

2: methanol / 5 h / Reflux

3: hydrazine hydrate / methanol / Reflux

4: methanol / Reflux

5: mercury(II) oxide / ethanol / 2 h / Reflux

With sodium methylate; sodium; hydrazine hydrate; mercury(II) oxide; In methanol; diethyl ether; ethanol;
DOI:10.2174/15734064113096660044