2-[7-(2,4-dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazole-3-carboxylic acid methyl ester

Base Information

• Chemical Name: 2-[7-(2,4-dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazole-3-carboxylic acid methyl ester
• CAS No.: 952235-61-9
• Molecular Formula: C₁₉H₁₅Cl₂N₅O₂
• Molecular Weight: 416.266

Synonyms:2-[7-(2,4-dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazole-3-carboxylic acid methyl ester

Chemical Property of 2-[7-(2,4-dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazole-3-carboxylic acid methyl ester

Chemical Property:

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Technology Process of 2-[7-(2,4-dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazole-3-carboxylic acid methyl ester

There total 1 articles about 2-[7-(2,4-dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazole-3-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloromethyl-7-(2,4-dichlorophenyl)-2-methyl-2H-indazole (952236-37-2) → 2-[7-(2,4-dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazole-3-carboxylic acid methyl ester (952235-61-9) + 1-[7-(2,4-dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-1H-[1,2,4]triazole-3-carboxylic acid methyl ester

Guidance literature:

methyl 1H-1,2,4-triazole-3-carboxylate; With sodium hydride; In N,N-dimethyl-formamide; for 0.166667h;

3-chloromethyl-7-(2,4-dichlorophenyl)-2-methyl-2H-indazole; In N,N-dimethyl-formamide; at 80 ℃; for 0.75h;

Reference yield: 85.0%

2-[7-(2,4-dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazole-3-carboxylic acid methyl ester (952235-61-9) → 2-[7-(2,4-Dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazole-3-carboxylic acid amide

Guidance literature:

With sodium cyanide; ammonia; In methanol; at 50 ℃;

Reference yield: 51.0%

2-[7-(2,4-dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazole-3-carboxylic acid methyl ester (952235-61-9) → 2-[7-(2,4-Dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazol-3-yl-methanol (952236-32-7)

Guidance literature:

With lithium borohydride; In methanol;

upstream raw materials:

3-chloromethyl-7-(2,4-dichlorophenyl)-2-methyl-2H-indazole

Downstream raw materials:

2-[7-(2,4-Dichlorophenyl)-2-methyl-2H-indazol-3-ylmethyl]-2H-[1,2,4]triazol-3-yl-methanol

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