2-Amino-N-phenethylacetamide hydrochloride

Base Information

• Chemical Name: 2-Amino-N-phenethylacetamide hydrochloride
• CAS No.: 55677-60-6
• Molecular Formula: C₁₀H₁₄N₂O*ClH
• Molecular Weight: 214.695
• Mol file: 55677-60-6.mol

Synonyms:α-amino-N-(2-phenylethyl)acetamide hydrochloride

Chemical Property of 2-Amino-N-phenethylacetamide hydrochloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

2-amino-N-phenethylacetamidehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Amino-N-phenethylacetamide hydrochloride

There total 4 articles about 2-Amino-N-phenethylacetamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl N-{[(2-phenylethyl)carbamoyl]methyl}carbamate (613675-75-5) → α-amino-N-(2-phenylethyl)acetamide hydrochloride (55677-60-6)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 0 - 20 ℃;

DOI:10.1016/S0960-894X(00)00458-3

Reference yield: 89.0%

(Phenethylcarbamoyl-methyl)-carbamic acid benzyl ester (55677-50-4) → α-amino-N-(2-phenylethyl)acetamide hydrochloride (55677-60-6)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; diethyl ether; for 6h; Ambient temperature;

DOI:10.1021/jm00357a007

Reference yield:

phenethylamine (64-04-0) → α-amino-N-(2-phenylethyl)acetamide hydrochloride (55677-60-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / acetonitrile / 2 h / 25 °C

2: 89 percent / H₂, HCl / 10 percent Pd/C / methanol; diethyl ether / 6 h / Ambient temperature

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; diethyl ether; acetonitrile;

DOI:10.1021/jm00357a007

upstream raw materials:

(Phenethylcarbamoyl-methyl)-carbamic acid benzyl ester

tert-butyl N-{[(2-phenylethyl)carbamoyl]methyl}carbamate

phenethylamine

Downstream raw materials:

C₃₆H₄₇N₉O₉S

(R)-5-Guanidino-2-phenylmethanesulfonylamino-pentanoic acid ({(S)-1-benzyl-2-hydroxy-2-[(phenethylcarbamoyl-methyl)-carbamoyl]-ethylcarbamoyl}-methyl)-methyl-amide

N-<<1-<(benzyloxycarbonyl)amino>-2-phenylethyl>-methoxyphosphinyl>-glycyl-2-phenylethylamine