(E)-3-phenylthioacrylic acid S-isopropyl ester

Base Information

• Chemical Name: (E)-3-phenylthioacrylic acid S-isopropyl ester
• CAS No.: 63877-31-6
• Molecular Formula: C₁₂H₁₄OS
• Molecular Weight: 206.309
• Mol file: 63877-31-6.mol

Synonyms:(E)-3-phenylthioacrylic acid S-isopropyl ester

Chemical Property of (E)-3-phenylthioacrylic acid S-isopropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-phenylthioacrylic acid S-isopropyl ester

There total 2 articles about (E)-3-phenylthioacrylic acid S-isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-propanethiol (75-33-2) + phenylacetylene (536-74-3) + molybdenum hexacarbonyl (13939-06-5,199620-15-0) → (E)-3-phenylthioacrylic acid S-isopropyl ester (63877-31-6)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In N,N-dimethyl-formamide; at 100 ℃; regioselective reaction;

DOI:10.1016/j.jorganchem.2016.01.025

Reference yield:

→ (E)-3-phenylthioacrylic acid S-isopropyl ester (63877-31-6)

Guidance literature:

α-Silylthiolester (1b), Benzaldehyd;

DOI:10.1016/S0040-4039(01)92842-4

Reference yield:

(E)-3-phenylthioacrylic acid S-isopropyl ester (63877-31-6) + 1,1-Diphenyl-3,4-dihydro-2H-1λ5-phosphole (113705-06-9) → trans-[4-(isopropylthio)-2-phenyl-4-cyclohepten-1-yl]diphenylphosphine oxide

Guidance literature:

In toluene; for 40h; Heating;

DOI:10.1021/jo990528q

upstream raw materials:

2-propanethiol

phenylacetylene

molybdenum hexacarbonyl