Thiamphenicol glycinate

Base Information

• Chemical Name: Thiamphenicol glycinate
• CAS No.: 2393-92-2
• Deprecated CAS: 14434-24-3,29963-28-8,36708-15-3,51514-22-8
• Molecular Formula: C₁₄H₁₈Cl₂N₂O₆S
• Molecular Weight: 413.279
• UNII: W5H94CY6V6
• DSSTox Substance ID: DTXSID7048326
• Wikidata: Q27292335
• ChEMBL ID: CHEMBL2365673
• Mol file: 2393-92-2.mol

Synonyms:thiamphenicol glycinate;thiamphenicol glycinate monohydrochloride, (R-(R*,R*))-isomer

Chemical Property of Thiamphenicol glycinate

Chemical Property:

• Melting Point: 163-166oC
• Boiling Point: 672.5 °C at 760 mmHg
• PKA: 10.70±0.46(Predicted)
• Flash Point: 360.5 °C
• PSA: 144.17000
• Density: 1.468 g/cm³
• LogP: 2.08590
• Storage Temp.: 0-6°C
• Solubility.: ethanol: 50 mg/mL, clear, colorless
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 9
• Exact Mass: 412.0262629
• Heavy Atom Count: 25
• Complexity: 558

Purity/Quality:

99% ^*data from raw suppliers

THIAMPHENICOL GLYCINATE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)C1=CC=C(C=C1)C(C(COC(=O)CN)NC(=O)C(Cl)Cl)O
• Isomeric SMILES: CS(=O)(=O)C1=CC=C(C=C1)[C@H]([C@@H](COC(=O)CN)NC(=O)C(Cl)Cl)O

Technology Process of Thiamphenicol glycinate

There total 2 articles about Thiamphenicol glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Thiamphenicolglycinat (97378-26-2,2393-92-2,29963-28-8,36708-15-3,51514-22-8)

Guidance literature:

d-threo-1-(p-Methylsulfonyl-phenyl)-2-dichlor-acetamido-1,3-propandiol(I)-monochloressigsaeureester, 1) Hexamethylentetramin, MeCN, 2) konz. HCl, Et2O;

Reference yield:

→ Thiophenikolglycinat (1071761-13-1,2393-92-2,29963-28-8,36708-15-3,51514-22-8)

Guidance literature:

Acetessigesterenaminoglykokoll-Natriumsalz, 1) Thiophenikol, Chlorameisensaeure-ethylester 2)HCl;