LINCOMYCIN HYDROCHLORIDE

Base Information

• Chemical Name: LINCOMYCIN HYDROCHLORIDE
• CAS No.: 17017-22-0
• Molecular Formula: C₁₈H₃₄N₂O₆S
• Molecular Weight: 406.544
• Mol file: 17017-22-0.mol

Synonyms:L-threo-D-galacto-Octopyranoside,methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-,trans-a- (8CI);L-threo-a-D-galacto-Octopyranoside, methyl6,8-dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-,(2S-trans)-;(7S)-Lincomycin;7-Deoxy-7(S)-hydroxylincomycin;7-Epilincomycin;Epilincomycin;Lincomycin, (7S)-;U 20244E;

Chemical Property of LINCOMYCIN HYDROCHLORIDE

Chemical Property:

• Boiling Point: 646.8±55.0 °C(Predicted)
• PKA: 12.91±0.70(Predicted)
• PSA: 147.79000
• Density: 1.29
• LogP: -0.52820
• Storage Temp.: 2-8°C
• Solubility.: H2O: 50 mg/mL, clear, colorless

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s): R36/37/38:
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: An epimer of Lincomycin (L466200); a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity. A less potent bactericidal than its (7R)-epimer.

Technology Process of LINCOMYCIN HYDROCHLORIDE

There total 3 articles about LINCOMYCIN HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ lincomycin (154-21-2,17017-22-0,35410-84-5,145920-50-9)

Guidance literature:

Lincomycin-hydrochlorid, entonisiertes W. 1)verd. wss. NaOH, pH10, 2) Chloroform, Extraktion; enthaelt 1,5percent W.;

DOI:10.1021/ja00986a035

Reference yield:

→ <15N>-Lincomycin (154-21-2,17017-22-0,35410-84-5,145920-50-9)

Guidance literature:

Clindamycin, Abbau;

DOI:10.1002/jps.2600590110

Reference yield:

→ opt.-inakt. Lincomycin (154-21-2,17017-22-0,35410-84-5,145920-50-9)

Guidance literature:

opt.-inakt. 1-Methyl-4ξ-n-propylprolin-hydrochlorid (21), Tri-n-butylamin, Acetonitril, Chlorameisensaeure-isobutylester, Methyl-thiolincosaminid (2);

DOI:10.1021/ja00986a038

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