(E)-2-Carboxymethoxy-3-(4-chloro-phenyl)-4-phenyl-but-2-enoic acid methyl ester

Base Information

Chemical Name:(E)-2-Carboxymethoxy-3-(4-chloro-phenyl)-4-phenyl-but-2-enoic acid methyl ester
CAS No.:74314-13-9
Molecular Formula:C₁₉H₁₇ClO₅
Molecular Weight:360.794
Hs Code.:

Synonyms:(E)-2-Carboxymethoxy-3-(4-chloro-phenyl)-4-phenyl-but-2-enoic acid methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-2-Carboxymethoxy-3-(4-chloro-phenyl)-4-phenyl-but-2-enoic acid methyl ester

Chemical Property:

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Technology Process of (E)-2-Carboxymethoxy-3-(4-chloro-phenyl)-4-phenyl-but-2-enoic acid methyl ester

There total 1 articles about (E)-2-Carboxymethoxy-3-(4-chloro-phenyl)-4-phenyl-but-2-enoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 7040-23-5
dimethyl diglycolate

: 1889-71-0
4'-chloro-2-phenylacetophenone

: 74314-13-9
(E)-2-Carboxymethoxy-3-(4-chloro-phenyl)-4-phenyl-but-2-enoic acid methyl ester

: 74314-14-0
(Z)-2-Carboxymethoxy-3-(4-chloro-phenyl)-4-phenyl-but-2-enoic acid methyl ester

Guidance literature:: With sodium hydride; In benzene; at 60 - 70 ℃; Yield given;

Reference yield:

: 74314-13-9
(E)-2-Carboxymethoxy-3-(4-chloro-phenyl)-4-phenyl-but-2-enoic acid methyl ester

: 74314-27-5
(3-Benzyl-6-chloro-1-oxo-1H-inden-2-yloxy)-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 10percent aq. NaOH / 3 h / Heating

2: (CH₃CO)2O / 12 h / Heating

3: AlCl₃ / nitrobenzene / 6 h / 30 °C

With sodium hydroxide; aluminium trichloride; acetic anhydride; In nitrobenzene;

Reference yield:

: 74314-13-9
(E)-2-Carboxymethoxy-3-(4-chloro-phenyl)-4-phenyl-but-2-enoic acid methyl ester

: 74318-54-0
3-[1-(4-Chloro-phenyl)-2-phenyl-eth-(E)-ylidene]-[1,4]dioxane-2,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 10percent aq. NaOH / 3 h / Heating

2: (CH₃CO)2O / 12 h / Heating

With sodium hydroxide; acetic anhydride;