(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid

Base Information

Chemical Name:(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid
CAS No.:62893-24-7
Molecular Formula:C15H17N3O6
Molecular Weight:335.316
Hs Code.:
European Community (EC) Number:625-629-3
Nikkaji Number:J27.882C
Wikidata:Q76146037
Mol file:62893-24-7.mol

Synonyms:62893-24-7;(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid;(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetic acid;(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetic acid;(R)-(-)-alpha-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic acid;C15H17N3O6;OH-EPCP;MFCD00792472;(2r)-2-((4-ethyl-2,3-dioxopiperazinyl)carbonylamino)-2-(4-hydroxyphenyl)acetic acid;SCHEMBL9567734;IPARGUVYMOMVNU-LLVKDONJSA-N;AKOS015895736;AC-8402;CS-W009844;(R)-(-)--[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic Acid;(alphaR)-alpha-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneacetic Acid;DS-11399;E0994;H10891;(R)-(-)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetic Acid;(R)-(-)-a-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)-carbonyl]amino]-4-hydroxybenzeneacetic acid;(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)aceticacid;[R,(?)]-(4-Ethyl-2,3-dioxo-1-piperazinylcarbonylamino)(4-hydroxyphenyl)acetic acid;(R)-(-)- alpha -[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic acid (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid;(R)-(-)-alpha-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic acid, 97%

Suppliers and Price of (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneaceticAcid
25 g
$ 175.00

TCI Chemical
(R)-(-)-alpha-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic Acid >98.0%(HPLC)(T)
1g
$ 24.00

TCI Chemical
(R)-(-)-alpha-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic Acid >98.0%(HPLC)(T)
5g
$ 86.00

Sigma-Aldrich
(R)-(?)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic acid 97%
5g
$ 111.00

Crysdot
(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)aceticacid 95+%
100g
$ 277.00

Chem-Impex
(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)aceticacid,98%(HPLC) 98%(HPLC)
5G
$ 112.00

American Custom Chemicals Corporation
(2R)-(-)-2-[(4-ETHYL-2,3-DIOXOPIPERAZINYL)CARBONYLAMINO]-2-(4-HYDROXYPHENYL)ACETIC ACID 95.00%
1G
$ 544.00

Ambeed
(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)aceticacid 96%
100g
$ 290.00

Ambeed
(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)aceticacid 96%
5g
$ 33.00

Ambeed
(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)aceticacid 96%
1g
$ 11.00

Total 98 raw suppliers

Chemical Property of (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid

Chemical Property:

Appearance/Colour:white crystalline powder
Melting Point:205 °C (dec.)(lit.)
Refractive Index:1.5600 (estimate)
Boiling Point:471.96°C (rough estimate)
PKA:3.40±0.10(Predicted)
PSA：127.25000
Density:1.456 g/cm³
LogP:0.18490
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:DMSO (Slightly), Methanol (Sparingly)
XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:335.11173527
Heavy Atom Count:24
Complexity:529

Purity/Quality:

NLT 99% ^*data from raw suppliers

(αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneaceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)O
Isomeric SMILES:CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)O
Uses (αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneacetic Acid is an intermediate used to prepare Cephalosporin derivatives with activities against both Gram-positive and Gram-negative bacteria.

Technology Process of (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid

There total 1 articles about (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.5%