N-benzyl-1-(4-methoxyphenyl)propan-2-amine;(2R)-2-hydroxy-2-phenylacetic acid

Base Information

Chemical Name:N-benzyl-1-(4-methoxyphenyl)propan-2-amine;(2R)-2-hydroxy-2-phenylacetic acid
CAS No.:245759-64-2
Molecular Formula:C₈H₈O₃*C₁₇H₂₁NO
Molecular Weight:407.51
Hs Code.:2922509090
European Community (EC) Number:607-405-7
Mol file:245759-64-2.mol

Synonyms:245759-64-2

Suppliers and Price of N-benzyl-1-(4-methoxyphenyl)propan-2-amine;(2R)-2-hydroxy-2-phenylacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-Benzyl-1-(4-methoxyphenyl)propan-2-amine(S)-2-hydroxy-2-phenylacetate 95+%
1g
$ 376.00

Total 24 raw suppliers

Chemical Property of N-benzyl-1-(4-methoxyphenyl)propan-2-amine;(2R)-2-hydroxy-2-phenylacetic acid

Chemical Property:

Vapor Pressure:6.58E-06mmHg at 25°C
Refractive Index:1.553
Boiling Point:377.8 °C at 760 mmHg
Flash Point:160.3 °C
PSA：21.26000
Density:1.025 g/cm³
LogP:3.80690
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:407.20965841
Heavy Atom Count:30
Complexity:368

Purity/Quality:

99% ^*data from raw suppliers

N-Benzyl-1-(4-methoxyphenyl)propan-2-amine(S)-2-hydroxy-2-phenylacetate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC=C(C=C1)OC)NCC2=CC=CC=C2.C1=CC=C(C=C1)C(C(=O)O)O
Isomeric SMILES:CC(CC1=CC=C(C=C1)OC)NCC2=CC=CC=C2.C1=CC=C(C=C1)[C@H](C(=O)O)O

Technology Process of N-benzyl-1-(4-methoxyphenyl)propan-2-amine;(2R)-2-hydroxy-2-phenylacetic acid

There total 8 articles about N-benzyl-1-(4-methoxyphenyl)propan-2-amine;(2R)-2-hydroxy-2-phenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17199-29-0
(S)-Mandelic acid

: 1049695-95-5
benzyl-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-amine; hydrochloride

: 245759-64-2
(R)-N-benzyl-N-(1-methyl-2-p-methoxyphenylethyl)amine L-mandelate

Guidance literature:: benzyl-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-amine; hydrochloride; With sodium hydroxide; In water;

(S)-Mandelic acid; In methanol; at 25 - 30 ℃; Resolution of racemate; Reflux;

Reference yield:

: 122-84-9
4-methoxybenzyl methyl ketone

: 17199-29-0
(S)-Mandelic acid

: 100-46-9
benzylamine

: 245759-64-2
N-benzyl-1-(4-methoxyphenyl)propan-2-amine mandalate salt

Guidance literature:: 4-methoxybenzyl methyl ketone; benzylamine; In methanol; at 25 - 45 ℃; for 2h; Autoclave; Large scale;

With platinum(IV) oxide; hydrogen; In methanol; at 25 - 30 ℃; Autoclave; Large scale;

(S)-Mandelic acid; In methanol; at 70 - 75 ℃; Large scale;

Reference yield:

: 122-84-9
4-methoxybenzyl methyl ketone

: 245759-64-2
(R)-N-benzyl-N-(1-methyl-2-p-methoxyphenylethyl)amine L-mandelate

Guidance literature:: Multi-step reaction with 2 steps

1: platinum on carbon; hydrogen / methanol / 20 °C / 2327.23 - 2844.39 Torr / Inert atmosphere

2: methanol / 20 °C / Inert atmosphere; Reflux

With platinum on carbon; hydrogen; In methanol;