Technology Process of C19H13Cl2NO4
There total 9 articles about C19H13Cl2NO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: N-chloro-succinimide / acetonitrile / 3 h / 20 °C
2.1: potassium hexamethylsilazane / acetonitrile / 20 °C
2.2: 0 - 20 °C
3.1: trifluoroacetic acid / 2 h / 20 °C
4.1: thionyl chloride / toluene / 3 h / 120 °C
4.2: 0 °C
With
N-chloro-succinimide; thionyl chloride; potassium hexamethylsilazane; trifluoroacetic acid;
In
toluene; acetonitrile;
- Guidance literature:
-
5-(2-chloro-4-methoxycarbonylmethyl-phenyl)-3-phenyl-isoxazole-4-carboxylic acid;
With
thionyl chloride;
In
toluene;
at 120 ℃;
for 3h;
With
triethylamine;
In
toluene;
at 0 ℃;
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: sulfuric acid / Heating / reflux
2.1: triethylamine / dichloromethane / 2 h / 0 °C
3.1: tetrakis(triphenylphosphine) palladium(0) / DMF (N,N-dimethyl-formamide) / 34 h / 80 °C
4.1: Raney-alloy / 10 h / 110 °C
5.1: tin(ll) chloride / dichloromethane / 6 h / 20 °C
6.1: potassium hexamethylsilazane / acetonitrile / 20 °C
6.2: 0 - 20 °C
7.1: trifluoroacetic acid / 2 h / 20 °C
8.1: thionyl chloride / toluene / 3 h / 120 °C
8.2: 0 °C
With
thionyl chloride; Raney-alloy; potassium hexamethylsilazane; triethylamine; trifluoroacetic acid; tin(ll) chloride;
tetrakis(triphenylphosphine) palladium(0); sulfuric acid;
In
DMF (N,N-dimethyl-formamide); dichloromethane; toluene; acetonitrile;
