Hydroxyapatite

Base Information

• Chemical Name: Hydroxyapatite
• CAS No.: 12167-74-7
• Deprecated CAS: 12440-80-1,136841-77-5,196875-13-5,1059174-00-3,221359-86-0,205873-50-3,29796-40-5,1337-78-6,947383-76-8,1398505-50-4
• Molecular Formula: HCa5O13P3
• Molecular Weight: 1004.64
• Hs Code.: 2835260000
• European Community (EC) Number: 215-145-7,235-330-6
• UNII: 91D9GV0Z28
• DSSTox Substance ID: DTXSID50872537
• Wikipedia: Hydroxyapatite,Hydroxylapatite
• Wikidata: Q27271399
• NCI Thesaurus Code: C84224
• ChEMBL ID: CHEMBL2218916
• Mol file: 12167-74-7.mol

Synonyms:Alveograf;Calcitite;Calcium Hydroxyapatite;Durapatite;Hydroxyapatite;Hydroxyapatite, Calcium;Hydroxylapatite;Interpore 200;Interpore 500;Interpore-200;Interpore-500;Interpore200;Interpore500;Osprovit;Ossein Hydroxyapatite Compound;Ossein-Hydroxyapatite Compound;Ossopan;Osteogen;Periograf

Chemical Property of Hydroxyapatite

Chemical Property:

• Melting Point: 1100 °C(lit.)
• Boiling Point: 158 °C at 760 mmHg
• PSA: 311.24000
• Density: 1.038 g/mL at 25 °C
• LogP: 0.98120
• Storage Temp.: 2-8°C
• Solubility.: Soluble in 1 M Hydrochloric acid.
• Water Solubility.: 0.1 g/L (25℃)
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 0
• Exact Mass: 501.675955
• Heavy Atom Count: 21
• Complexity: 36.8

Purity/Quality:

99% ^*data from raw suppliers

Hydroxyapatite ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:
• Safety Statements: S24/25:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Metals, Inorganic Compounds
• Canonical SMILES: [OH-].[O-]P(=O)([O-])[O-].[O-]P(=O)([O-])[O-].[O-]P(=O)([O-])[O-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2]
• Recent ClinicalTrials: Effects of Calcium Hydroxylapatite on Cellulite Dimples in the Buttocks
• Uses: Si-substituted hydroxyapatite (Si-HAp) nanopowder can be incorporated in biodegradable polymer composites or deposited on biocompatible surfaces similar to pure HAp nanopowder (cat. no. 677418). Biological activity of HAp was shown to be enhanced by substitution of silicon ions into a fraction of HAp lattice phosphate sites.1,2 Hydroxyapatite nanopowders, incorporated in biodegradable polymer composites1 or deposited on biocompatible substrates,2 have been shown to promote adhesions and proliferation of bone-forming (osteoblast) cells. Utilized in powdered spices as an anticaking agent and baby powder. It is the starting material for the production of phosphoric acid and fertilizers. Employed in tissue replacement for repairing bony defects and act as drug carrier for drug delivery to the bone. Calcium phosphate tribasic (C3161) is plant cell culture tested (0.2 mg/ml) and is appropriate for use in plant cell culture experiments. Calcium phosphate tribasic is utilized to engineer new biomaterials for applications such as bone grafts and fillers.