2-(pyridin-2-yl)phenyl 2-naphthoate

Base Information

• Chemical Name: 2-(pyridin-2-yl)phenyl 2-naphthoate
• CAS No.: 1450914-90-5
• Molecular Formula: C₂₂H₁₅NO₂
• Molecular Weight: 325.367
• Mol file: 1450914-90-5.mol

Synonyms:2-(pyridin-2-yl)phenyl 2-naphthoate

Chemical Property of 2-(pyridin-2-yl)phenyl 2-naphthoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(pyridin-2-yl)phenyl 2-naphthoate

There total 3 articles about 2-(pyridin-2-yl)phenyl 2-naphthoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2-phenylpyridine (1008-89-5) + 2-methoxy-3-phenylbenzo[g]isoquinolin-1(2H)-one (76749-35-4) → 2-(pyridin-2-yl)phenyl 2-naphthoate (1450914-90-5)

Guidance literature:

With tert.-butylhydroperoxide; copper diacetate; In chlorobenzene; at 120 ℃; for 24h;

DOI:10.1055/s-0034-1378830

Reference yield: 44.0%

2-phenylpyridine (1008-89-5) + 2-naphthoic peroxyanhydride (38512-20-8) → 2-(pyridin-2-yl)phenyl 2-naphthoate (1450914-90-5)

Guidance literature:

With palladium diacetate; In 5,5-dimethyl-1,3-cyclohexadiene; at 130 ℃; for 3.5h; regioselective reaction;

DOI:10.3390/molecules18044403

Reference yield:

2-naphthaloyl chloride (2243-83-6) → 2-(pyridin-2-yl)phenyl 2-naphthoate (1450914-90-5)

Guidance literature:

Multi-step reaction with 2 steps

1: dihydrogen peroxide; sodium hydroxide / water

2: palladium diacetate / 5,5-dimethyl-1,3-cyclohexadiene / 3.5 h / 130 °C

With dihydrogen peroxide; palladium diacetate; sodium hydroxide; In 5,5-dimethyl-1,3-cyclohexadiene; water;

DOI:10.3390/molecules18044403

upstream raw materials:

2-phenylpyridine

2-naphthoic peroxyanhydride

2-naphthaloyl chloride

2-methoxy-3-phenylbenzo[g]isoquinolin-1(2H)-one