Triammonium triiron tetracitrate

Base Information

• Chemical Name: Triammonium triiron tetracitrate
• CAS No.: 1185-57-5
• Molecular Formula: C6H8O7.xFe.xH3N
• Molecular Weight: 279.99
• Hs Code.: 29181500
• European Community (EC) Number: 214-686-6,257-857-0
• UN Number: 3077
• DSSTox Substance ID: DTXSID20200363
• Wikipedia: Ammonium_ferric_citrate
• RXCUI: 24897
• Mol file: 1185-57-5.mol

Synonyms:ferric ammonium citrate

Chemical Property of Triammonium triiron tetracitrate

Chemical Property:

• Appearance/Colour: Ferric ammonium citrate is a yellowish brown to red solid with a faint odor of ammonia.
• Vapor Pressure: 0Pa at 25℃
• Boiling Point: 197oC
• PSA: 102.37000
• Density: 1.8 g/cm3 (20oC)
• LogP: -1.15840
• Storage Temp.: Store at RT.
• Sensitive.: Hygroscopic
• Solubility.: 1200g/l
• Water Solubility.: 1200 g/L (20 ºC)
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 28
• Rotatable Bond Count: 8
• Exact Mass: 977.922039
• Heavy Atom Count: 58
• Complexity: 211

Purity/Quality:

99% ^*data from raw suppliers

Ferric Ammonium Citrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Metals, Inorganic Compounds
• Canonical SMILES: C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[NH4+].[NH4+].[NH4+].[Fe+3].[Fe+3].[Fe+3]
• Uses: 1.? Nutritional supplements. Iron enhancer, anti-anemia iron agent (each oral 1~2g). It can be added to biscuits, milk powder, being not suitable for being applied to food that is not colored. 2.? Ammonium ferric citrate, as a food iron fortifier, has its absorption effect be better than inorganic iron. China provides that it can be used for salt and sandwich sugar with the usage amount of 4000~8000mg/kg; in high-iron cereal and its products (daily limit: 50 g of such food): 1200~1350mg/kg; dairy and infant food: 400 to 800 mg/kg; in cereals and their products, 160 to 330 mg/kg; beverages: 70 to 140 mg/kg. 3.? It can be used for the pharmaceutical industry 4.? It is used in the photographic industry and the pharmaceutical industry 5.? It can be used as the nutritional supplements (iron fortifier). For dairy products, bread and wheat flour. Also used as anti-caking agent. 6.? It can be used in bacterial culture medium for measuring aluminum, photography, blue print, blood and so on. 7.? The brown product can be used as a hematinic drug for the treatment of iron deficiency anemia; it can be used as food additives; according to the provision of Japanese, "Food Additives", iron content: 16.5%-21.2%. The brown product and green product are both chemical-sensitive substances with the green goods being more sensitive to light than brown goods. Paper coated with green ferric ammonium citrate and red blood salt (potassium ferricyanide) is called blue blueprint paper. Upon the exposure, the trivalent iron in the citric acid salt is converted to bivalent, coming across water to give turnbull's blue, so the lightened part exhibits blue color while the rest part is still white, yielding a blue matrix white line pattern. Hematinic For blueprints; in photography. Ferric Ammonium Citrate is a nutrient supplement that is a source of iron. It is prepared by the reaction of ferric hydroxide with citric acid, followed by treatment with ammonium hydroxide, evaporation, and drying. The resulting product occurs in two forms, i.e., brown with 16.5–18.5% iron and ferric ammonium citrate, green with 14.5–16% iron. Iron Ammonium Citrate is an anticaking agent used in salt. It is the chemical green ferric ammonium citrate.
• Production method: The ferric hydroxide is dissolved in citric acid, neutralized with ammonia solution, followed by drying to obtain it. (1) Preparation of ferric hydroxide Ferrous sulfate was added to the water, and sulfuric acid was slowly added thereto under stirring, followed by addition of an aqueous sodium chlorate solution. Then stir vigorously and raise the temperature to above 80 ℃; further add sodium chlorate. Stir until the reaction is terminated (no further ferrous reaction through ferricyanide test) to obtain the ferric sulfate solution. Add this solution to the reaction tank, add sodium hydroxide solution and stir vigorously with the reaction temperature of 80-90 °; when the reaction solution turns from viscous to thin, add water for washing until the sulfate and chlorine meet the requirements. Dry to get the iron hydroxide. (2) Preparation of ferric ammonium citrate; add citrate, ferric hydroxide and water into the reaction tank, stir and control the temperature at 95 ℃ above and maintain the temperature for 1h. And then cooled to 50?C and sent into ammonia under stirring. Stand for more than 48h. The supernatant was filtered and the filtrate was concentrated to a paste and dried at 80 ° C to obtain ferric ammonium citrate. The total yield of ferrous sulfate is 73-75%. The same procedure as in preparation method 2 of brown ferric ammonium citrate. Adding ammonium hydroxide to the ferric sulfate to generate ferrous hydroxide precipitate; filter and wash with water to no sulfate reaction anymore; then add? citrate and heat to 60?C to completely dissolve the precipitate; neutralize with ammonia hydroxide and concentrate to a syrupy state, and coat on a glass plate, and dry to obtain a small sheet product. Fe2 (SO4) 3 + 6NH3 + 6H2O → 3 (NH4) 2SO4 + 2Fe (OH) 3 ↓ 2C6H8O7 + 3NH4OH + Fe (OH) 3 → (C6H5O7) 2Fe (NH4) 3 + 6H2O It can also taken of ferrous sulfate as raw materials. 28g FeSO4 ? 7H2O was dissolved in 4 mL water; add 3 mL 98% concentrated sulfuric acid and then drop 5mL 36% hydrogen peroxide; heat to 83 ℃ and stir for 0.5h; the blue color upon potassium ferricyanide test can tell the termination of the reaction; further add 100 mL distilled water, and 40% NaOH was added at 80 ° C with stirring to make the solution be alkaline. The precipitate was suction filtered and washed with hot water until no sulfate was present any more. The prepared Fe (OH) 3 was added to a citric acid solution (14 g/100 mL water) and stirred at 95 ° C for 1 h. The solution was then cooled to 50 ° C and an appropriate amount of aqueous ammonia was added. The solution was cooled to room temperature. Evaporate the supernatant to a paste with drying at 60~80 ° C to obtain the product with a yield of 91%. A considerable amount of citric acid solution was added to ferric hydroxide produced from reaction between the ferric sulfate and aqueous ammonia; the concentrated slurry was coated on a glass plate, dried, and then peeled off from the glass plate. Ferric hydroxide is dissolved in citric acid, with neutralization with ammonia hydroxide and evaporation at 60 ° C to obtain.
• Description: Ammonium ferric citrate is a food additive with E number E381 used as an acidity regulator. It is a green or reddish-brown powder which is very soluble in water. The molecular formula of ammonium iron (III) citrate is variable. It can be prepared by adding Fe(OH)3 to an aqueous solution of citric acid and ammonia . The brown form is approximately 9% NH3, 16.5 – 18.5 % Fe , and 65 % hydrated citric acid; the green form is approximately 7.5 % NH3 , 14.5 – 16 % Fe, and 75% hydrated citric acid. The green type is more readily reduced by light than the brown. Other uses for ammonium ferric citrate include water purification and printing (cyano type). It is used as a reducing agent of metal salts of low activity like gold and silver and is also in a commonly used recipe with potassium ferricyanide to make cyanotype prints. Ammonium ferric citrate is also used in Kligler iron deeps to determine hydrogen sulfide production in microbial metabolism. In medicine, ammonium ferric citrate is used as a contrast medium. It is also used as a hematinic.