2,4-Dichloro-D-phenylalanine

Base Information

Chemical Name:2,4-Dichloro-D-phenylalanine
CAS No.:114872-98-9
Molecular Formula:C9H9Cl2NO2
Molecular Weight:234.08
Hs Code.:2922499990
European Community (EC) Number:800-082-5
DSSTox Substance ID:DTXSID80426365
Nikkaji Number:J2.638.859G
Wikidata:Q72467306
ChEMBL ID:CHEMBL4633276
Mol file:114872-98-9.mol

Synonyms:2,4-Dichloro-D-phenylalanine;114872-98-9;D-2,4-Dichlorophenylalanine;(2R)-2-amino-3-(2,4-dichlorophenyl)propanoic acid;D-Phenylalanine, 2,4-dichloro-;(R)-2-AMINO-3-(2,4-DICHLOROPHENYL)PROPANOIC ACID;CHEMBL4633276;MFCD01860873;(2R)-2-azaniumyl-3-(2,4-dichlorophenyl)propanoate;H-D-PHE(2,4-CL2)-OH;SCHEMBL1613174;DTXSID80426365;BDBM50541216;AKOS012010401;AKOS015850049;AC-5847;AM82014;CS-W012916;DS-0451;HY-W012200;PS-3748;EN300-199893;A803254;D-2,4-Dichlorophenylalanine (H-D-Phe(2,4-diCl)-OH)

Suppliers and Price of 2,4-Dichloro-D-phenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
D-2,4-Dichlorophenylalanine
500mg
$ 333.00

TRC
D-2,4-Dichlorophenylalanine
250mg
$ 55.00

Matrix Scientific
2,4-Dichloro-D-phenylalanine 95+%
1g
$ 208.00

Matrix Scientific
2,4-Dichloro-D-phenylalanine 95+%
10g
$ 805.00

Matrix Scientific
2,4-Dichloro-D-phenylalanine 95+%
5g
$ 559.00

Crysdot
2,4-Dichloro-D-phenylalanine 97%
25g
$ 251.00

ChemPep
H-D-Phe(2,4-DiCl)-OH
5g
$ 270.00

ChemPep
H-D-Phe(2,4-DiCl)-OH
25g
$ 810.00

Chem-Impex
D-2,4-Dichlorophenylalanine,99%(HPLC) 99%(HPLC)
1G
$ 72.80

Chem-Impex
D-2,4-Dichlorophenylalanine ≥ 99% (HPLC)
25G
$ 795.00

Total 61 raw suppliers

Chemical Property of 2,4-Dichloro-D-phenylalanine

Chemical Property:

Boiling Point:368.1 °C at 760 mmHg
PKA:2.14±0.15(Predicted)
Flash Point:176.4 °C
PSA：63.32000
Density:1.45 g/cm³
LogP:2.64810
Storage Temp.:Store at 0-5°C
XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:233.0010339
Heavy Atom Count:14
Complexity:213

Purity/Quality:

99% ^*data from raw suppliers

D-2,4-Dichlorophenylalanine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)Cl)CC(C(=O)O)N
Isomeric SMILES:C1=CC(=C(C=C1Cl)Cl)C[C@H](C(=O)O)N

Technology Process of 2,4-Dichloro-D-phenylalanine

There total 2 articles about 2,4-Dichloro-D-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 5472-68-4
rac-2,4-dichloro-Phe

: 114872-98-9
2,4-dichloro-D-phenylalanine

Guidance literature:: With sodium hydroxide; oxygen; 2-amino-2-hydroxymethyl-1,3-propanediol; In water; at 30 ℃; for 3h; pH=7.3; enantioselective reaction; Resolution of racemate; Enzymatic reaction;
DOI:10.1016/j.tetlet.2008.08.111

Reference yield:

: 444726-81-2
2-acetamido-3-(2,4-dichlorophenyl)propionic acid

: 114872-98-9
2,4-dichloro-D-phenylalanine

: 111119-36-9
(S)-2-amino-3-(2,4-dichlorophenyl)propanoic acid

Guidance literature:: With hydrogenchloride; In water; at 95 - 100 ℃; for 6h; Overall yield = 62 %;
DOI:10.1080/00397911.2012.748075

Reference yield:

: 50768-69-9
5-hydroxydihydrofuran-2(3H)-one

: 114872-98-9
2,4-dichloro-D-phenylalanine

: 1110540-26-5
C₁₃H₁₅Cl₂NO₄

Guidance literature:: 5-hydroxydihydrofuran-2(3H)-one; 2,4-dichloro-D-phenylalanine; In tetrahydrofuran; water; at 20 ℃; for 1h;

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; water; for 10h;