Chemical Property of Ferrous Fumarate
Chemical Property:
- Appearance/Colour:orange red to reddish-brown powder with no odour and no taste
- Vapor Pressure:0Pa at 25℃
- Melting Point:>280 ºC
- PSA：52.60000
- Density:2.435 g/cm3
- LogP:-0.44490
- Storage Temp.:Refrigerator
- Solubility.:Slightly soluble in water, very slightly soluble in ethanol (96 per cent).
- Water Solubility.:Soluble in water (0.14 g/100 ml at 25°C).
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:0
- Exact Mass:169.930244
- Heavy Atom Count:9
- Complexity:108
- Purity/Quality:
-
98% *data from raw suppliers
Iron(II) fumarate *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- Statements:
36/37/38
- Safety Statements:
22-36/37/39-24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C(=CC(=O)[O-])C(=O)[O-].[Fe+2]
- Isomeric SMILES:C(=C/C(=O)[O-])\C(=O)[O-].[Fe+2]
- Recent ClinicalTrials:Do Iron Supplements Impact the Gut Microbiome of Women of Reproductive Age?
- Recent EU Clinical Trials:Daily versus alternate day oral iron supplementation for the treatment of iron deficiency anaemia in pregnancy (IronWoman)
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Uses
Iron(II) Fumarate is a a chemical used in the treatment of iron deficiency. More commonly used for this treatment is Ferrous Sulfate however Iron(II) Fumarate does maintain similar absorption profiles. Ferrous fumarate is available as a syrup and may be useful in small children for the treatment and prophylaxis of iron deficiency. Ferrous Fumarate is a reddish orange to red-brown powder that is a
source of iron. it has high bioavailability and can be used in foods
where the red color can be masked. it contains approximately 33%
iron. it is used as a dietary supplement in breakfast cereals, poultry
stuffing, enriched flour, and instant drinks. Iron(II) fumarate is used as dietary Supplement, nutrient, iron source in foods and pharmaceuticals, as animal feed additive and in infant formulas.
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Description
Ferrous fumarate is the ferrous salt form of fumarate. One of its most important applications is being used as iron supplements for the treatment of iron deficiency and anemia. It has been demonstrated that application of ferrous sulfate drops or a single daily dose of microencapsulated ferrous fumarate sprinkles plus ascorbic acid both result in successful treatment of anemia without remarkable side effects. However, recent studies have also shown that compared to other iron supplements, ferrous fumarate has a highest rate of inducing adverse reactions such as erosive mucosal injury in the gastrointestinal tract as well as nausea, vomiting and epigastric discomfort.
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Therapeutic Function
Hematinic
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Clinical Use
Iron deficiency anaemia
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Drug interactions
Potentially hazardous interactions with other drugs
Antibacterials: reduced absorption of 4-quinolones
and tetracyclines.
Dimercaprol: avoid concomitant use.
Mycophenolate: may significantly reduce absorption
of mycophenolate.
