9-[2'-bis(4-dimethylaminophenyl)hydroxymethylbiphenyl-2-yl]-9-hydroxyxanthene

Base Information

• Chemical Name: 9-[2'-bis(4-dimethylaminophenyl)hydroxymethylbiphenyl-2-yl]-9-hydroxyxanthene
• CAS No.: 216655-41-3
• Molecular Formula: C₄₂H₃₈N₂O₃
• Molecular Weight: 618.775
• Mol file: 216655-41-3.mol

Synonyms:9-[2'-bis(4-dimethylaminophenyl)hydroxymethylbiphenyl-2-yl]-9-hydroxyxanthene

Chemical Property of 9-[2'-bis(4-dimethylaminophenyl)hydroxymethylbiphenyl-2-yl]-9-hydroxyxanthene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 9-[2'-bis(4-dimethylaminophenyl)hydroxymethylbiphenyl-2-yl]-9-hydroxyxanthene

There total 4 articles about 9-[2'-bis(4-dimethylaminophenyl)hydroxymethylbiphenyl-2-yl]-9-hydroxyxanthene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

bis(p-methoxyphenyl)methanone (90-96-0) + biphenyl-2,2'-diyl-bis-lithium (16291-32-0) → 2,2'-bis[bis(4-dimethylaminophenyl)hydroxymethyl]biphenyl (194494-00-3) + 2,2'-bis[bis(p-methoxyphenyl)hydroxymethyl]biphenyl (194494-02-5) + 9-[2'-bis(4-dimethylaminophenyl)hydroxymethylbiphenyl-2-yl]-9-hydroxyxanthene (216655-41-3)

Guidance literature:

With bis(p-dimethylaminophenyl)methanone; Title compound not separated from byproducts;

DOI:10.1039/a806037a

Reference yield: 8.6%

xanth-9-one (90-47-1) + bis(p-dimethylaminophenyl)methanone (90-94-8) + 2,2'-diiodobiphenyl (2236-52-4) → 2,2'-bis[bis(4-dimethylaminophenyl)hydroxymethyl]biphenyl (194494-00-3) + biphenyl-2,2'-diylbis(9-hydroxyxanthene) + 9-[2'-bis(4-dimethylaminophenyl)hydroxymethylbiphenyl-2-yl]-9-hydroxyxanthene (216655-41-3)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at 20 ℃; for 2h;

DOI:10.1021/jo0003697

Reference yield: 8.0%

xanth-9-one (90-47-1) + biphenyl-2,2'-diyl-bis-lithium (16291-32-0) → 2,2'-bis[bis(4-dimethylaminophenyl)hydroxymethyl]biphenyl (194494-00-3) + biphenyl-2,2'-diylbis(9-hydroxyxanthene) + 9-[2'-bis(4-dimethylaminophenyl)hydroxymethylbiphenyl-2-yl]-9-hydroxyxanthene (216655-41-3)

Guidance literature:

With bis(p-dimethylaminophenyl)methanone; Title compound not separated from byproducts;

DOI:10.1039/a806037a

upstream raw materials:

xanth-9-one

bis(p-dimethylaminophenyl)methanone

biphenyl-2,2'-diyl-bis-lithium

bis(p-methoxyphenyl)methanone

Downstream raw materials:

spiro[10,10-bis(4-dimethylaminophenyl)-9,10-dihydrophenanthrene-9,9'-[9H]xanthene]