methyl 4-[3-(4-trifluoromethoxyphenyl)-2-oxo-5-oxazolidinyl]methoxybenzoate

Base Information

Chemical Name:methyl 4-[3-(4-trifluoromethoxyphenyl)-2-oxo-5-oxazolidinyl]methoxybenzoate
CAS No.:154871-31-5
Molecular Formula:C₁₉H₁₆F₃NO₆
Molecular Weight:411.334
Hs Code.:

Synonyms:methyl 4-[3-(4-trifluoromethoxyphenyl)-2-oxo-5-oxazolidinyl]methoxybenzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 4-[3-(4-trifluoromethoxyphenyl)-2-oxo-5-oxazolidinyl]methoxybenzoate

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Technology Process of methyl 4-[3-(4-trifluoromethoxyphenyl)-2-oxo-5-oxazolidinyl]methoxybenzoate

There total 2 articles about methyl 4-[3-(4-trifluoromethoxyphenyl)-2-oxo-5-oxazolidinyl]methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 5535-03-5
methyl rac-4-(oxiran-2-ylmethoxy)benzoate

: 35037-73-1
1-isocyanato-4-trifluoromethoxy-benzene

: 154871-31-5
methyl 4-[3-(4-trifluoromethoxyphenyl)-2-oxo-5-oxazolidinyl]methoxybenzoate

Guidance literature:: With Tributylphosphine oxide; lithium bromide; In xylene; at 140 ℃; for 2h;
DOI:10.1002/ardp.200400920

Reference yield:

: 99-76-3,156291-94-0
methyl 4-hydroxylbenzoate

: 154871-31-5
methyl 4-[3-(4-trifluoromethoxyphenyl)-2-oxo-5-oxazolidinyl]methoxybenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / K₂CO₃ / dimethylformamide / 70 °C

2: 93 percent / LiBr*H₂O; tri-n-butylphosphine oxide / xylene / 2 h / 140 °C

With Tributylphosphine oxide; potassium carbonate; lithium bromide; In N,N-dimethyl-formamide; xylene;
DOI:10.1002/ardp.200400920