(E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-yl diisopropylcarbamate

Base Information

Chemical Name:(E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-yl diisopropylcarbamate
CAS No.:1384881-33-7
Molecular Formula:C₂₉H₄₃NO₃Si
Molecular Weight:481.751
Hs Code.:

Synonyms:(E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-yl diisopropylcarbamate

Suppliers and Price of (E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-yl diisopropylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-yl diisopropylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-yl diisopropylcarbamate

There total 2 articles about (E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-yl diisopropylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 19009-39-3
N,N-diisopropylcarbamoyl chloride

: 157063-00-8
(E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-ol

: 1384881-33-7
(E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-yl diisopropylcarbamate

Guidance literature:: (E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-ol; With potassium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 0.416667h; Inert atmosphere;

N,N-diisopropylcarbamoyl chloride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1016/j.tet.2012.05.103

Reference yield:

: 88158-68-3
4-(tert-butyldiphenylsilyloxy)-1-butyne

: 1384881-33-7
(E)-6-[(tert-butyldiphenylsilyl)oxy]hex-3-en-2-yl diisopropylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: sodium bis(2-methoxyethoxy)aluminium dihydride / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere

3.1: potassium hydride / tetrahydrofuran; mineral oil / 0.42 h / 0 - 20 °C / Inert atmosphere

3.2: 0.5 h / 20 °C / Inert atmosphere

With n-butyllithium; potassium hydride; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; hexane; mineral oil;
DOI:10.1016/j.tet.2012.05.103