N-(2-bromo-phenyl)-N-(4-methoxy-benzyl)-2-(4-chloro-benzyl)-acrylamide

Base Information

• Chemical Name: N-(2-bromo-phenyl)-N-(4-methoxy-benzyl)-2-(4-chloro-benzyl)-acrylamide
• CAS No.: 1047670-64-3
• Molecular Formula: C₂₄H₂₁BrClNO₂
• Molecular Weight: 470.793

Synonyms:N-(2-bromo-phenyl)-N-(4-methoxy-benzyl)-2-(4-chloro-benzyl)-acrylamide

Chemical Property of N-(2-bromo-phenyl)-N-(4-methoxy-benzyl)-2-(4-chloro-benzyl)-acrylamide

Chemical Property:

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Technology Process of N-(2-bromo-phenyl)-N-(4-methoxy-benzyl)-2-(4-chloro-benzyl)-acrylamide

There total 1 articles about N-(2-bromo-phenyl)-N-(4-methoxy-benzyl)-2-(4-chloro-benzyl)-acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H21BrClNO4 → C23H21BrClNO2 + N-(2-bromo-phenyl)-N-(4-methoxy-benzyl)-2-(4-chloro-benzyl)-acrylamide (1047670-64-3)

Guidance literature:

With formaldehyd; diethylamine; In N,N-dimethyl-formamide; at 62 ℃; Cooling with ice;

DOI:10.1002/anie.200800549

Reference yield: 64.0%

N-(2-bromo-phenyl)-N-(4-methoxy-benzyl)-2-(4-chloro-benzyl)-acrylamide (1047670-64-3) → C24H20ClNO2 (1047670-71-2)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; caesium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 24h; Inert atmosphere;

DOI:10.1002/anie.200800549

Downstream raw materials:

C₂₄H₂₀ClNO₂

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