(1S^*,10R^*)-10-Hydroxy-1,11,11-trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.0^2,6>undec-8-en-3,5-dion

Base Information

• Chemical Name: (1S^*,10R^*)-10-Hydroxy-1,11,11-trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.0^2,6>undec-8-en-3,5-dion
• CAS No.: 100084-56-8
• Molecular Formula: C₁₇H₁₉N₃O₃
• Molecular Weight: 313.356
• Mol file: 100084-56-8.mol

Synonyms:(1S^*,10R^*)-10-Hydroxy-1,11,11-trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.0^2,6>undec-8-en-3,5-dion

Chemical Property of (1S^*,10R^*)-10-Hydroxy-1,11,11-trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.0^2,6>undec-8-en-3,5-dion

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S^*,10R^*)-10-Hydroxy-1,11,11-trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.0^2,6>undec-8-en-3,5-dion

There total 2 articles about (1S^*,10R^*)-10-Hydroxy-1,11,11-trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.0^2,6>undec-8-en-3,5-dion which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

1,11,11-Trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.02,6>undec-8-en-3,5,10-trion (100084-46-6) → (1S*,10S*)-10-Hydroxy-1,11,11-trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.02,6>undec-8-en-3,5-dion (100164-19-0) + (1S*,10R*)-10-Hydroxy-1,11,11-trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.02,6>undec-8-en-3,5-dion (100084-56-8)

Guidance literature:

With sodium tetrahydroborate; In ethanol; water; isopropyl alcohol; for 3h; Ambient temperature;

Reference yield:

4-Phenyl-1,2,4-triazolidine-3,5-dione (4233-33-4) → (1S*,10R*)-10-Hydroxy-1,11,11-trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.02,6>undec-8-en-3,5-dion (100084-56-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / benzene / 2 h / Heating

2: 13 percent / NaBH₄ / ethanol; propan-2-ol; H₂O / 3 h / Ambient temperature

With sodium tetrahydroborate; In ethanol; water; isopropyl alcohol; benzene;

Reference yield: 74.0%

(1S*,10R*)-10-Hydroxy-1,11,11-trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.02,6>undec-8-en-3,5-dion (100084-56-8) → 11,11-Dimethyl-7-methylen-4-phenyl-2,4,6-triazatricyclo<6.2.1.02,6>undec-9-en-3,5-dion (100084-65-9)

Guidance literature:

With trichlorophosphate; In pyridine; at 110 ℃; for 2.5h;

upstream raw materials:

1,11,11-Trimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.0^2,6>undec-8-en-3,5,10-trion

4-Phenyl-1,2,4-triazolidine-3,5-dione

Downstream raw materials:

11,11-Dimethyl-7-methylen-4-phenyl-2,4,6-triazatricyclo<6.2.1.0^2,6>undec-9-en-3,5-dion

Refernces