2-(2-isopropylpiperazin-1-yl)-4-(4-(methoxymethyl)phenyl)-1,3,5-triazine

Base Information

Chemical Name:2-(2-isopropylpiperazin-1-yl)-4-(4-(methoxymethyl)phenyl)-1,3,5-triazine
CAS No.:1580440-88-5
Molecular Formula:C₁₈H₂₅N₅O
Molecular Weight:327.429
Hs Code.:

Synonyms:2-(2-isopropylpiperazin-1-yl)-4-(4-(methoxymethyl)phenyl)-1,3,5-triazine

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Chemical Property of 2-(2-isopropylpiperazin-1-yl)-4-(4-(methoxymethyl)phenyl)-1,3,5-triazine

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Technology Process of 2-(2-isopropylpiperazin-1-yl)-4-(4-(methoxymethyl)phenyl)-1,3,5-triazine

There total 3 articles about 2-(2-isopropylpiperazin-1-yl)-4-(4-(methoxymethyl)phenyl)-1,3,5-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1580440-87-4
tert-butyl 3-isopropyl-4-(4-(4-(methoxymethyl)phenyl)-1,3,5-triazin-2-yl)piperazine-1-carboxylate

: 1580440-88-5
2-(2-isopropylpiperazin-1-yl)-4-(4-(methoxymethyl)phenyl)-1,3,5-triazine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 3h;

Reference yield:

: 502649-32-3
tert-butyl 3-isopropylpiperazine-1-carboxylate

: 1580440-88-5
2-(2-isopropylpiperazin-1-yl)-4-(4-(methoxymethyl)phenyl)-1,3,5-triazine

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / tetrahydrofuran / 0 - 20 °C

2: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; XPhos / 1,4-dioxane / 16 h / 140 °C

3: trifluoroacetic acid / dichloromethane / 3 h / 0 °C

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium carbonate; caesium carbonate; trifluoroacetic acid; XPhos; In tetrahydrofuran; 1,4-dioxane; dichloromethane;

Reference yield:

: 1580440-86-3
tert-butyl 4-(4-chloro-1,3,5-triazin-2-yl)-3-isopropylpiperazine-1-carboxylate

: 1580440-88-5
2-(2-isopropylpiperazin-1-yl)-4-(4-(methoxymethyl)phenyl)-1,3,5-triazine

Guidance literature:: Multi-step reaction with 2 steps

1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; XPhos / 1,4-dioxane / 16 h / 140 °C

2: trifluoroacetic acid / dichloromethane / 3 h / 0 °C

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; trifluoroacetic acid; XPhos; In 1,4-dioxane; dichloromethane;