Technology Process of C22H28ClN5O5S
There total 10 articles about C22H28ClN5O5S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C22H27ClN4O5S;
With
acetic acid; sodium nitrite;
In
water;
at 0 ℃;
With
amalgamated zinc;
In
water;
at 0 ℃;
for 5h;
With
sodium carbonate;
In
water;
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 16 h
2.1: isopropyl alcohol / 16 h / Reflux
3.1: dmap / tetrahydrofuran / 16 h / Reflux
4.1: hydrazine / ethanol / 3 h / Reflux
5.1: dmap; diisopropyl-carbodiimide / chloroform / 0 - 20 °C
6.1: dichloromethane; 1,4-dioxane / 1 h / 20 °C
7.1: sodium cyanoborohydride / N,N-dimethyl-formamide; methanol / 16 h / 20 °C
8.1: sodium nitrate / water; acetic acid / 0.5 h / 0 °C
8.2: 5 h / 0 °C
With
dmap; sodium nitrate; hydrogen; sodium cyanoborohydride; hydrazine; diisopropyl-carbodiimide;
palladium 10% on activated carbon;
In
tetrahydrofuran; 1,4-dioxane; methanol; ethanol; dichloromethane; chloroform; water; acetic acid; ethyl acetate; N,N-dimethyl-formamide; isopropyl alcohol;
- Guidance literature:
-
Multi-step reaction with 10 steps
1.1: dmap / acetonitrile / 16 h / Reflux
2.1: potassium carbonate / methanol / 16 h / Reflux
3.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 16 h
4.1: isopropyl alcohol / 16 h / Reflux
5.1: dmap / tetrahydrofuran / 16 h / Reflux
6.1: hydrazine / ethanol / 3 h / Reflux
7.1: dmap; diisopropyl-carbodiimide / chloroform / 0 - 20 °C
8.1: dichloromethane; 1,4-dioxane / 1 h / 20 °C
9.1: sodium cyanoborohydride / N,N-dimethyl-formamide; methanol / 16 h / 20 °C
10.1: sodium nitrate / water; acetic acid / 0.5 h / 0 °C
10.2: 5 h / 0 °C
With
dmap; sodium nitrate; hydrogen; sodium cyanoborohydride; potassium carbonate; hydrazine; diisopropyl-carbodiimide;
palladium 10% on activated carbon;
In
tetrahydrofuran; 1,4-dioxane; methanol; ethanol; dichloromethane; chloroform; water; acetic acid; ethyl acetate; N,N-dimethyl-formamide; isopropyl alcohol; acetonitrile;
