4-Chloro-3-pyridinesulfonamide

Base Information

Chemical Name:4-Chloro-3-pyridinesulfonamide
CAS No.:33263-43-3
Molecular Formula:C5H5ClN2O2S
Molecular Weight:192.626
Hs Code.:29333999
European Community (EC) Number:251-434-4
UNII:QY6G99E6Q2
DSSTox Substance ID:DTXSID50186904
Nikkaji Number:J319.520A
Wikidata:Q72458566
Mol file:33263-43-3.mol

Synonyms:4-Chloro-3-pyridylsulfonamide;

Suppliers and Price of 4-Chloro-3-pyridinesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-3-pyridinesulfonamide
500mg
$ 55.00

SynQuest Laboratories
4-Chloropyridine-3-sulfonamide
10 g
$ 77.00

SynQuest Laboratories
4-Chloropyridine-3-sulfonamide
25 g
$ 138.00

Medical Isotopes, Inc.
4-Chloropyridine-3-sulfonamide 98%
100 g
$ 550.00

Matrix Scientific
4-Chloropyridine-3-sulphonamide >95%
1g
$ 30.00

Crysdot
4-Chloropyridine-3-sulfonamide 98%
100g
$ 197.00

Chemenu
4-Chloropyridine-3-sulphonamide 98%
100g
$ 194.00

Biosynth Carbosynth
4-Chloro-3-pyridinesulfonamide
100 g
$ 284.00

Biosynth Carbosynth
4-Chloro-3-pyridinesulfonamide
50 g
$ 163.00

Ark Pharm
4-Chloropyridine-3-sulfonamide 98%
10g
$ 51.00

Total 117 raw suppliers

Chemical Property of 4-Chloro-3-pyridinesulfonamide

Chemical Property:

Appearance/Colour:off-white to light beige powder
Vapor Pressure:5.46E-06mmHg at 25°C
Melting Point:150-155 °C
Refractive Index:1.592
Boiling Point:380.4 °C at 760 mmHg
PKA:9.01±0.60(Predicted)
Flash Point:183.9 °C
PSA：81.43000
Density:1.558 g/cm³
LogP:2.16350
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
Water Solubility.:soluble
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:191.9760263
Heavy Atom Count:11
Complexity:223

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-3-pyridinesulfonamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 36/37/38-22
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=CC(=C1Cl)S(=O)(=O)N
Uses 4-Chloro-3-pyridinesulfonamide is a building block that has been used as a reactant for the preparation of heterocyclic 4-substituted pyridine-3-sulfonamide derivatives as inhibitors of four isoforms of zinc enzyme carbonic anhydrase.

Technology Process of 4-Chloro-3-pyridinesulfonamide

There total 4 articles about 4-Chloro-3-pyridinesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 33263-44-4
4-chloro-pyridine-3-sulfonyl chloride

: 33263-43-3
4-chloropyridine-3-sulphonamide

Guidance literature:: With ammonium hydroxide;
DOI:10.1021/jm00073a025

Reference yield:

: 51498-37-4
4-hydroxypyridine-3-sulfonic acid

: 33263-43-3
4-chloropyridine-3-sulphonamide

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃, PCl₅

2: NH₄OH

With ammonium hydroxide; phosphorus pentachloride; trichlorophosphate;
DOI:10.1021/jm00073a025