1,5-di(2-furyl)-3-(2-methoxyphenyl)-2-methyl-1,5-pentanedione

Base Information

• Chemical Name: 1,5-di(2-furyl)-3-(2-methoxyphenyl)-2-methyl-1,5-pentanedione
• CAS No.: 83463-02-9
• Molecular Formula: C₂₁H₂₀O₅
• Molecular Weight: 352.387
• Mol file: 83463-02-9.mol

Synonyms:1,5-di(2-furyl)-3-(2-methoxyphenyl)-2-methyl-1,5-pentanedione

Chemical Property of 1,5-di(2-furyl)-3-(2-methoxyphenyl)-2-methyl-1,5-pentanedione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,5-di(2-furyl)-3-(2-methoxyphenyl)-2-methyl-1,5-pentanedione

There total 1 articles about 1,5-di(2-furyl)-3-(2-methoxyphenyl)-2-methyl-1,5-pentanedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-propionylfuran (3194-15-8) + (E)-1-(furan-2-yl)-3 (2-methoxyphenyl)-2-propen-1-one (111042-61-6) → 1,5-di(2-furyl)-3-(2-methoxyphenyl)-2-methyl-1,5-pentanedione (83463-02-9)

Guidance literature:

With sodium hydroxide; In methanol; at 25 ℃; for 40h;

DOI:10.1021/jo00145a048

Reference yield: 71.0%

1,5-di(2-furyl)-3-(2-methoxyphenyl)-2-methyl-1,5-pentanedione (83463-02-9) → 2,6-di(2-furyl)-4-(2-methoxyphenyl)-3-methylpyridine (83463-07-4)

Guidance literature:

With hydroxylamine hydrochloride; In butan-1-ol; for 6h; Heating;

DOI:10.1021/jo00145a048

Reference yield:

1,5-di(2-furyl)-3-(2-methoxyphenyl)-2-methyl-1,5-pentanedione (83463-02-9) → 4-(2-methoxyphenyl)-3-methylpyridine-2,6-dicarboxylic acid (83463-11-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 71 percent / hydroxylamine hydrochloride / butan-1-ol / 6 h / Heating

2: 90 percent / KMnO₄ / acetone / 96 h / 25 °C

With potassium permanganate; hydroxylamine hydrochloride; In acetone; butan-1-ol;

DOI:10.1021/jo00145a048

upstream raw materials:

2-propionylfuran

(E)-1-(furan-2-yl)-3 (2-methoxyphenyl)-2-propen-1-one

Downstream raw materials:

2,6-di(2-furyl)-4-(2-methoxyphenyl)-3-methylpyridine

4-(2-methoxyphenyl)-3-methylpyridine-2,6-dicarboxylic acid

4-(2-methoxyphenyl)-3-methylpyridine