2-Chloro-4-fluorobenzothiazole

Base Information

Chemical Name:2-Chloro-4-fluorobenzothiazole
CAS No.:182344-56-5
Molecular Formula:C7H3ClFNS
Molecular Weight:187.62
Hs Code.:29342000
DSSTox Substance ID:DTXSID40365948
Wikidata:Q72450601
Mol file:182344-56-5.mol

Synonyms:2-Chloro-4-fluorobenzothiazole;182344-56-5;2-chloro-4-fluorobenzo[d]thiazole;2-chloro-4-fluoro-1,3-benzothiazole;MFCD04448820;Benzothiazole, 2-chloro-4-fluoro-;2-Chloro-4-fluoro-benzothiazole;SCHEMBL2634141;2-chloro-4-fluoro benzothiazole;DTXSID40365948;VCSYBEOXGIHVTR-UHFFFAOYSA-N;AKOS005208049;CS-W021651;AM807323;AS-18173;FT-0649111;EN300-237625;F1910-0007

Suppliers and Price of 2-Chloro-4-fluorobenzothiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-4-fluorobenzothiazole
1g
$ 280.00

SynQuest Laboratories
2-Chloro-4-fluoro-1,3-benzothiazole
1 g
$ 117.00

Matrix Scientific
2-Chloro-4-fluorobenzothiazole 95+%
10g
$ 1340.00

Matrix Scientific
2-Chloro-4-fluorobenzothiazole 95+%
5g
$ 998.00

Matrix Scientific
2-Chloro-4-fluorobenzothiazole 95+%
1g
$ 347.00

Crysdot
2-Chloro-4-fluorobenzo[d]thiazole 95+%
10g
$ 375.00

Crysdot
2-Chloro-4-fluorobenzo[d]thiazole 95+%
5g
$ 221.00

Chemenu
2-Chloro-4-fluorobenzothiazole 95%
5g
$ 238.00

Chemenu
2-Chloro-4-fluorobenzothiazole 95%
10g
$ 358.00

Chemenu
2-Chloro-4-fluorobenzothiazole 95%
25g
$ 823.00

Total 45 raw suppliers

Chemical Property of 2-Chloro-4-fluorobenzothiazole

Chemical Property:

Vapor Pressure:0.036mmHg at 25°C
Refractive Index:1.637
Boiling Point:253 °C at 760 mmHg
Flash Point:106.8 °C
PSA：41.13000
Density:1.532 g/cm³
LogP:3.08880
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:186.9658761
Heavy Atom Count:11
Complexity:157

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-4-fluorobenzothiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C2C(=C1)SC(=N2)Cl)F

Technology Process of 2-Chloro-4-fluorobenzothiazole

There total 3 articles about 2-Chloro-4-fluorobenzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 154327-24-9
4-fluoro-2-mercaptobenzothiazole

: 182344-56-5
2-chloro-4-fluoro benzothiazole

Guidance literature:: With sulfuryl dichloride; In dichloromethane; at 20 ℃; for 1h; Cooling with ice;
DOI:10.1016/j.bmc.2015.11.011

Reference yield: 67.0%

: 182344-56-5
2-chloro-4-fluoro benzothiazole

Guidance literature:: With sulfuryl dichloride; In dichloromethane; at 22 ℃; for 1h; Cooling with ice;

Reference yield:

: 5509-65-9
2,6-difluoroaniline

: 182344-56-5
2-chloro-4-fluoro benzothiazole

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 3.5 h / 120 °C / Inert atmosphere

2: sulfuryl dichloride / dichloromethane / 1 h / 20 °C / Cooling with ice

With sulfuryl dichloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2015.11.011