C₁₇H₁₇NO₃

Base Information

• Chemical Name: C₁₇H₁₇NO₃
• CAS No.: 754990-74-4
• Molecular Formula: C₁₇H₁₇NO₃
• Molecular Weight: 283.327
• Mol file: 754990-74-4.mol

Synonyms:C₁₇H₁₇NO₃

Chemical Property of C₁₇H₁₇NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₇NO₃

There total 12 articles about C₁₇H₁₇NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

C11H12O2 → C17H17NO3 (754990-74-4)

Guidance literature:

With dmap; In acetonitrile; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1039/c8ob01915k

Reference yield:

C13H18O3 → C17H17NO3 (754990-74-4)

Guidance literature:

Multi-step reaction with 7 steps

1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

1.2: 3 h / 20 °C / Inert atmosphere

2.1: 9-borabicyclo[3.3.1]nonane dimer / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

2.2: 3 h / 0 °C / Inert atmosphere

3.1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

4.1: 2,2'-azobis(isobutyronitrile) / toluene / 10 h / 85 °C / Inert atmosphere

5.1: dichloromethane; methanol / 21 h / Irradiation; Inert atmosphere

6.1: acetyl chloride / acetonitrile / 3 h / 20 °C / Inert atmosphere

7.1: dmap / acetonitrile / 1 h / 20 °C / Inert atmosphere

With dmap; 9-borabicyclo[3.3.1]nonane dimer; 2,2'-azobis(isobutyronitrile); sodium hydride; sodium hydrogencarbonate; Dess-Martin periodane; acetyl chloride; In tetrahydrofuran; methanol; dichloromethane; toluene; acetonitrile;

DOI:10.1039/c8ob01915k

Reference yield:

C16H24O4 → C17H17NO3 (754990-74-4)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 9-borabicyclo[3.3.1]nonane dimer / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

1.2: 3 h / 0 °C / Inert atmosphere

2.1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

3.1: 2,2'-azobis(isobutyronitrile) / toluene / 10 h / 85 °C / Inert atmosphere

4.1: dichloromethane; methanol / 21 h / Irradiation; Inert atmosphere

5.1: acetyl chloride / acetonitrile / 3 h / 20 °C / Inert atmosphere

6.1: dmap / acetonitrile / 1 h / 20 °C / Inert atmosphere

With dmap; 9-borabicyclo[3.3.1]nonane dimer; 2,2'-azobis(isobutyronitrile); sodium hydrogencarbonate; Dess-Martin periodane; acetyl chloride; In tetrahydrofuran; methanol; dichloromethane; toluene; acetonitrile;

DOI:10.1039/c8ob01915k

upstream raw materials:

(4R,5aS,7aS,7bR)-5,5a,6,7,7a,7b-hexahydro-7b-hydroxy-4-methyl-indeno[1,7-bc]furan-2(4H)-one

Refernces

• 1、 Von Nussbaum, Franz,Hanke, Roman,Fahrig, Thomas,Benet-Buchholz, Jordi. "The high-intrinsic diels-alder reactivity of (-)-galiellalactone; generating four quaternary carbon centers under mild conditions". . p. 2783 - 2790. Retrieved 2007/10/03.