-3-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzoquinolizine

Chemical Name:(2R, 3R, 11bS)-(+)-8-benzyloxy-2-<(4,9-dihydro-3H-pyrido<3,4b>indol-1-yl)methyl>-3-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzoquinolizine

CAS No.:69437-62-3
Molecular Formula:C₃₆H₄₁N₃O₃
Molecular Weight:563.74
Hs Code.:

(2R, 3R, 11bS)-(+)-8-benzyloxy-2-<(4,9-dihydro-3H-pyrido<3,4b>indol-1-yl)methyl>-3-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzo<a>quinolizine

Synonyms:(2R, 3R, 11bS)-(+)-8-benzyloxy-2-<(4,9-dihydro-3H-pyrido<3,4b>indol-1-yl)methyl>-3-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzoquinolizine

Suppliers and Price of (2R, 3R, 11bS)-(+)-8-benzyloxy-2-<(4,9-dihydro-3H-pyrido<3,4b>indol-1-yl)methyl>-3-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzo quinolizine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemical Property of (2R, 3R, 11bS)-(+)-8-benzyloxy-2-<(4,9-dihydro-3H-pyrido<3,4b>indol-1-yl)methyl>-3-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzoquinolizine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R, 3R, 11bS)-(+)-8-benzyloxy-2-<(4,9-dihydro-3H-pyrido<3,4b>indol-1-yl)methyl>-3-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzo quinolizine

There total 7 articles about (2R, 3R, 11bS)-(+)-8-benzyloxy-2-<(4,9-dihydro-3H-pyrido<3,4b>indol-1-yl)methyl>-3-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzo quinolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 69461-01-4
(2R, 3R, 11bS)-(+)-8-benzyloxy-3-ethyl-1,3,4,6,7,11b-hexahydro-N-<2-(indol-3-yl)ethyl>-9,10-dimethoxy-2H-benzo quinolizine-2-acetamide

: 69437-62-3
(2R, 3R, 11bS)-(+)-8-benzyloxy-2-<(4,9-dihydro-3H-pyrido<3,4b>indol-1-yl)methyl>-3-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzo quinolizine

Guidance literature:: With trichlorophosphate; In toluene; for 2.5h; Heating;
DOI:10.1248/cpb.33.1946

Reference yield:

: 65891-86-3,69461-01-4
(+/-)-8-benzyloxy-3α-ethyl-1,3,4,6,7,11bα-hexahydro-N-<2-(indol-3-yl)ethyl>-9,10-dimethoxy-2H-benzo quinolizine-2β-acetamide

: 69437-62-3,101064-84-0
(+/-)-8-benzyloxy-2β-<(4,9-dihydro-3H-pyrido<3,4b>indol-1-yl)methyl>-3α-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzo quinolizine

Guidance literature:: With trichlorophosphate; In toluene; for 2.5h; Yield given; Heating;
DOI:10.1248/cpb.33.1946

Reference yield:

: 61-54-1
tryptamine

: 69437-62-3,101064-84-0
(+/-)-8-benzyloxy-2β-<(4,9-dihydro-3H-pyrido<3,4b>indol-1-yl)methyl>-3α-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzo quinolizine

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / diethyl phosphorocyanidate, Et₃N / dimethylformamide / 6 h / 30 °C

2: POCl₃ / toluene / 2.5 h / Heating

With diethyl cyanophosphonate; triethylamine; trichlorophosphate; In N,N-dimethyl-formamide; toluene;
DOI:10.1248/cpb.33.1946