N-[2-(tert-butyldimethylsiloxymethyl)allyl]-N-but-2-ynyl-4-methylbenzenesulfonamide

Base Information

Chemical Name:N-[2-(tert-butyldimethylsiloxymethyl)allyl]-N-but-2-ynyl-4-methylbenzenesulfonamide
CAS No.:365561-92-8
Molecular Formula:C₂₁H₃₃NO₃SSi
Molecular Weight:407.649
Hs Code.:

Synonyms:N-[2-(tert-butyldimethylsiloxymethyl)allyl]-N-but-2-ynyl-4-methylbenzenesulfonamide

Suppliers and Price of N-[2-(tert-butyldimethylsiloxymethyl)allyl]-N-but-2-ynyl-4-methylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[2-(tert-butyldimethylsiloxymethyl)allyl]-N-but-2-ynyl-4-methylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[2-(tert-butyldimethylsiloxymethyl)allyl]-N-but-2-ynyl-4-methylbenzenesulfonamide

There total 2 articles about N-[2-(tert-butyldimethylsiloxymethyl)allyl]-N-but-2-ynyl-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 286376-23-6
4-methyl-N-(prop-1-yn-1-yl)benzenesulfonamide

: 491879-65-3
methanesulfonic acid 2-(tert-butyl-dimethyl-silanyloxymethyl)allyl ester

: 365561-92-8
N-[2-(tert-butyldimethylsiloxymethyl)allyl]-N-but-2-ynyl-4-methylbenzenesulfonamide

Guidance literature:: 4-methyl-N-(prop-1-yn-1-yl)benzenesulfonamide; With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; at 0 ℃; for 1h;

methanesulfonic acid 2-(tert-butyl-dimethyl-silanyloxymethyl)allyl ester; With sodium iodide; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; Further stages.;
DOI:10.1002/1615-4169(200208)344:6/7<678::AID-ADSC678>3.0.CO;2-P

Reference yield:

: 116700-73-3
2-(tert-butyl-dimethyl-silanyloxymethyl)-prop-2-en-1-ol

: 365561-92-8
N-[2-(tert-butyldimethylsiloxymethyl)allyl]-N-but-2-ynyl-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 100 percent / Et₃N / CH₂Cl₂ / 0.17 h / -10 °C

2.1: NaH / tetrahydrofuran; dimethylformamide / 1 h / 0 °C

2.2: 71 percent / NaI / tetrahydrofuran; dimethylformamide / 20 °C

With sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/1615-4169(200208)344:6/7<678::AID-ADSC678>3.0.CO;2-P

Reference yield:

: 365561-92-8
N-[2-(tert-butyldimethylsiloxymethyl)allyl]-N-but-2-ynyl-4-methylbenzenesulfonamide

: 1015099-00-9
N-but-2-ynyl-(2-hydroxymethylallyl)-4-methylbenzenesulfonamide

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1002/1615-4169(200208)344:6/7<678::AID-ADSC678>3.0.CO;2-P