Technology Process of 2-(((1s,4s)-4-((3-methyl-5-phenyl-4-m-tolyl-1H-pyrazol-1-yl)methyl)cyclohexyl)methoxy)acetic acid
There total 1 articles about 2-(((1s,4s)-4-((3-methyl-5-phenyl-4-m-tolyl-1H-pyrazol-1-yl)methyl)cyclohexyl)methoxy)acetic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-bromo-5-methyl-3-phenyl-1H-pyrazole;
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 1h;
tert-butyl 2-(((1s,4s)-4-(tosyloxymethyl)cyclohexyl)methoxy)acetate;
In
N,N-dimethyl-formamide;
at 0 - 42 ℃;
m-tolylboronic acid;
With
potassium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
1,4-dioxane; water;
at 150 ℃;
for 4h;
Microwave irradiation;
