3-Diazo-4-hydroxy-3,4-dihydronaphthalene-1-sulfonyl chloride

Base Information

• Chemical Name: 3-Diazo-4-hydroxy-3,4-dihydronaphthalene-1-sulfonyl chloride
• CAS No.: 36451-09-9
• Molecular Formula: C10H5ClN2O3S
• Molecular Weight: 268.68
• Hs Code.: 2927000090
• UN Number: 3222
• Mol file: 36451-09-9.mol

Synonyms:3-Diazo-4-hydroxy-3,4-dihydronaphthalene-1-sulfonyl chloride;2-Diazo-1-naphthol-4-sulfonyl chloride;SCHEMBL5675229;AKOS015919815

Chemical Property of 3-Diazo-4-hydroxy-3,4-dihydronaphthalene-1-sulfonyl chloride

Chemical Property:

• Melting Point: 28-31°C
• Boiling Point: 215-217?°C30?mm Hg(lit.)
• Flash Point: >230?°F
• PSA: 96.98000
• Density: 1.107?g/mL?at 25?°C(lit.)
• LogP: 2.62506
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 269.9865910
• Heavy Atom Count: 17
• Complexity: 502
• Transport DOT Label: Flammable Solid

Purity/Quality:

98% ^*data from raw suppliers

2-Diazo-1-naphthol-4-sulphochloride 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C(=[N+]=[N-])C=C2S(=O)(=O)Cl)O
• Uses: 2-Diazo-1-naphthol-4-sulfonyl chloride is a useful research chemical.

Technology Process of 3-Diazo-4-hydroxy-3,4-dihydronaphthalene-1-sulfonyl chloride

There total 8 articles about 3-Diazo-4-hydroxy-3,4-dihydronaphthalene-1-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

→ 1,2-naphthoquinone-2-diazide-4-sulfonyl chloride (36451-09-9)

Guidance literature:

Reference yield: 80.0%

1,2-Naphthochinondiazid-(2)-4-sulfonsaeure Natriumsalz (64173-96-2) → 1,2-naphthoquinone-2-diazide-4-sulfonyl chloride (36451-09-9)

Guidance literature:

With triethylamine; trichloromethyl chloroformate; In dichloromethane; at -50 ℃; for 1.33333 - 1.5h; Product distribution / selectivity;

Reference yield:

2-amino-1-naphthol-4-sulfonic acid (567-13-5) → 1,2-naphthoquinone-2-diazide-4-sulfonyl chloride (36451-09-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / CuSO₄, NaNO₂ / H₂O / 0.17 h

2: 30 percent / chlorosulfonic acid / 1) 65 deg, 5h, 2) overnight

With chlorosulfonic acid; copper(II) sulfate; sodium nitrite; In water;

upstream raw materials:

1-hydroxy-4-sulfo-naphthalene-2-diazonium-betaine

2-diazo-1,2-naphthoquinone

1,2-Naphthochinondiazid-⁽²⁾-4-sulfonsaeure Natriumsalz

2-amino-1-naphthol-4-sulfonic acid

Downstream raw materials:

1-oxo-2-diazo-1,2-dihydronaphthalenesulfonic acid p-tolyl ester

phenyl naphthoquinone-1,2-(diazide-2)-4-sulfonate

decane

C₃₀H₂₂N₂O₅S