3-methyl-4-{4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl}-1-(4-methoxybenzyl)-1H-indole

Base Information

Chemical Name:3-methyl-4-{4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl}-1-(4-methoxybenzyl)-1H-indole
CAS No.:1384543-18-3
Molecular Formula:C₂₄H₂₃N₅O
Molecular Weight:397.48
Hs Code.:

Synonyms:3-methyl-4-{4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl}-1-(4-methoxybenzyl)-1H-indole

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Chemical Property of 3-methyl-4-{4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl}-1-(4-methoxybenzyl)-1H-indole

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Technology Process of 3-methyl-4-{4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl}-1-(4-methoxybenzyl)-1H-indole

There total 3 articles about 3-methyl-4-{4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl}-1-(4-methoxybenzyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazole dihydrochloride

: 1384543-16-1
4-bromo-1-(4-methoxybenzyl)-3-methyl-1H-indole

: 1384543-18-3
3-methyl-4-{4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl}-1-(4-methoxybenzyl)-1H-indole

Guidance literature:: With copper(I) oxide; caesium carbonate; N,N`-dimethylethylenediamine; In dimethyl sulfoxide; at 150 ℃; for 12h;

Reference yield:

: 824-94-2
p-methoxybenzyl chloride

: 1384543-18-3
3-methyl-4-{4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl}-1-(4-methoxybenzyl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h / 0 °C / Cooling with ice

1.2: 0.5 h / 70 °C

2.1: copper(I) oxide; N,N`-dimethylethylenediamine; caesium carbonate / dimethyl sulfoxide / 12 h / 150 °C

With copper(I) oxide; sodium hydride; caesium carbonate; N,N`-dimethylethylenediamine; In dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 475039-81-7
4-bromo-3-methyl-1H-indole

: 1384543-18-3
3-methyl-4-{4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl}-1-(4-methoxybenzyl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h / 0 °C / Cooling with ice

1.2: 0.5 h / 70 °C

2.1: copper(I) oxide; N,N`-dimethylethylenediamine; caesium carbonate / dimethyl sulfoxide / 12 h / 150 °C

With copper(I) oxide; sodium hydride; caesium carbonate; N,N`-dimethylethylenediamine; In dimethyl sulfoxide; N,N-dimethyl-formamide;