2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-, disodium salt

Base Information

• Chemical Name: 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-, disodium salt
• CAS No.: 5460-09-3
• Molecular Formula: C10H8NNaO7S2
• Molecular Weight: 341.298
• Hs Code.: 29222100
• European Community (EC) Number: 226-736-4,223-566-2,241-302-4
• DSSTox Substance ID: DTXSID9063247
• Mol file: 5460-09-3.mol

Synonyms:3963-80-2;H Acid disodium salt;EINECS 223-566-2;2,7-NAPHTHALENEDISULFONIC ACID, 4-AMINO-5-HYDROXY-, DISODIUM SALT;EPI-0023;Disodium 4-amino-5-hydroxy-2,7-naphthalenedisulfonate;disodium;4-amino-5-hydroxynaphthalene-2,7-disulfonate;Disodium 4-amino-5-hydroxynaphthalene-2,7-disulphonate;4-Amino-5-hydroxy-2,7-naphthalenedisulfonic acid sodium salt;Sodium 4-Amino-5-hydroxy-2,7-naphthalenedisulfonate;2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-, sodium salt (1:2);17265-34-8;5460-09-3;C10H7NNa2O7S2;C10H9NO7S2.2Na;SCHEMBL3100229;DTXSID9063247;PHIMTKWJUXQMMA-UHFFFAOYSA-L;SB83519;LS-94637;SODIUM 4-AMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONATE;SODIUM4-AMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONATE;4-Amino-5-hydroxy-2,7-naphthalenedisulfonic acid disodium salt

Chemical Property of 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-, disodium salt

Chemical Property:

• Appearance/Colour: Dark Gray Powder
• Melting Point: >300°C
• PSA: 183.81000
• Density: 1.88g/cm3
• LogP: 2.95690
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Water Solubility.: slightly soluble
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 0
• Exact Mass: 362.94593247
• Heavy Atom Count: 22
• Complexity: 535

Purity/Quality:

99.9% ^*data from raw suppliers

H acid ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C2C=C(C=C(C2=C(C=C1S(=O)(=O)[O-])N)O)S(=O)(=O)[O-].[Na+].[Na+]

Technology Process of 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-, disodium salt

There total 4 articles about 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-, disodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H6NO7S2(3-)*3Na(1+) + 1-aminonaphthalene-3,6,8-trisulphonic acid trisodium salt → C10H7NO7S2(2-)*2Na(1+) + disodium chromotropate (129-96-4) + 4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid disodium salt (3963-80-2,5460-09-3,17265-34-8,66108-97-2)

Guidance literature:

1-aminonaphthalene-3,6,8-trisulphonic acid trisodium salt; With sodium hydroxide; at 180 - 200 ℃;

C₁₀H₆NO₇S₂^(3-)*3Na⁽¹⁺⁾; With sulfuric acid; at 50 ℃; Autoclave;

Reference yield:

C10H6NO7S2(3-)*3Na(1+) → 4-amino-5-hydroxy-2,7-naphthalene-disulfonic acid, monosodium salt (5460-09-3)

Guidance literature:

With sulfuric acid;

Reference yield:

sodium salt of 1-nitronaphthalene-3,6,8-trisulphonic acid → 4-amino-5-hydroxy-2,7-naphthalene-disulfonic acid, monosodium salt (5460-09-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogen / 170 °C / 150015 Torr

2: sodium hydroxide / methanol / 180 - 200 °C / 21002.1 Torr

3: sulfuric acid

With sulfuric acid; hydrogen; sodium hydroxide; In methanol;

Downstream raw materials:

4,4'-[1,6-hexanediylbis(carbonylamino)]bis(5-hydroxy-2,7-naphthalenedisulfonic acid)

C₁₆H₁₀N₃O₁₀S₃^(3-)*3Na⁽¹⁺⁾

(E)-5-ammonio-3-(2-(4-carboxy-2-methylphenyl)hydrazono)-4-oxo-3,4-dihydronaphthalene-2,7-disulfonate

(E)-5-ammonio-3-(2-(4-carboxyphenyl)hydrazono)-4-oxo-3,4-dihydronaphthalene-2,7-disulfonate

Refernces

• 1、 -. "Method adopting clean process for preparing H-acid". . . Retrieved 2016/10/10.