Chemical Property of 4-Formylphenylboronic acid
Chemical Property:
- Appearance/Colour:white to light yellow crystal powder
- Vapor Pressure:0Pa at 25℃
- Melting Point:237-242 °C(lit.)
- Boiling Point:347.584 °C at 760 mmHg
- PKA:7.34±0.10(Predicted)
- Flash Point:164.013 °C
- PSA：57.53000
- Density:1.244 g/cm3
- LogP:-0.82110
- Storage Temp.:0-6°C
- Sensitive.:Air Sensitive
- Solubility.:<10g/l
- Water Solubility.:Slightly Soluble in water.
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:2
- Exact Mass:150.0488242
- Heavy Atom Count:11
- Complexity:130
- Purity/Quality:
-
>98% *data from raw suppliers
4-Formylphenylboronic acid
*data from reagent suppliers
Safty Information:
- Pictogram(s):
C,
Xi
- Hazard Codes:C,Xi
- Statements:
34-36/37/38
- Safety Statements:
22-26-36/37/39-45-37/39-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:B(C1=CC=C(C=C1)C=O)(O)O
-
Uses
suzuki reaction 4-Formylbenzeneboronic acid acts as a reagent used for Palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water, copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides, ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids, triethylamine-catalyzed three-component Hantzsch condensations, copper-catalyzed nitrations, oxidative mono-cleavage of dialkenes catalyzed by Trametes hirsuta, palladacycle-catalyzed cross-coupling of arylboronic acids with carboxylic anhydrides or acyl chlorides, palladium-catalyzed aerobic oxidative cross-coupling reactions. It acts as a reagent used in preparation of sensitizers with dithiafulvenyl unit as electron donor for high-efficiency dye-sensitized solar cells, a novel protein synthesis inhibitor active against Gram-positive bacteria. 4-Formylphenylboronic acid is a substrate for Suzuki cross-coupling reactions and it can be used as a reagent for:Palladium-catalyzed Suzuki-Miyaura cross-coupling in water. Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides. Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids. Triethylamine-catalyzed three-component Hantzsch condensations. Copper-catalyzed nitrations. Oxidative mono-cleavage of dialkenes catalyzed by Trametes hirsuta. Palladacycle-catalyzed cross-coupling of arylboronic acids with carboxylic anhydrides or acyl chlorides. Palladium-catalyzed aerobic oxidative cross-coupling reactions. The synthesis of sensitizers with dithiafulvenyl unit as electron donor for high-efficiency dye-sensitized solar cells.The synthesis of a novel protein synthesis inhibitor active against Gram-positive bacteria.The Suzuki aryl-aryl coupling of the upper rim of hexahomotrioxacalix[3]arene.A rhodium-catalyzed cyclization, converting 1,5-enynes to cyclopentenes and spiro-cyclopentenes.
