CID 657320

Base Information

Chemical Name:CID 657320
CAS No.:56296-78-7
Molecular Formula:C17H18F3NO^.HCl
Molecular Weight:345.792
Hs Code.:29222990

Synonyms:AKOS015896352

Suppliers and Price of CID 657320

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fluoxetine-d5 Hydrochloride
1mg
$ 425.00

TRC
Fluoxetine hydrochloride
25mg
$ 55.00

TRC
Fluoxetine hydrochloride
250mg
$ 175.00

Tocris
Fluoxetine hydrochloride ≥99%(HPLC)
50
$ 399.00

Tocris
Fluoxetine hydrochloride ≥99%(HPLC)
10
$ 98.00

TCI Chemical
Fluoxetine Hydrochloride >98.0%(HPLC)(T)
5g
$ 218.00

TCI Chemical
Fluoxetine Hydrochloride >98.0%(HPLC)(T)
1g
$ 73.00

Sigma-Aldrich
Fluoxetine hydrochloride United States Pharmacopeia (USP) Reference Standard
200mg
$ 366.00

Sigma-Aldrich
Fluoxetine hydrochloride solid
50mg
$ 365.00

Sigma-Aldrich
Fluoxetine, Hydrochloride - CAS 56296-78-7 - Calbiochem
25mg
$ 238.65

Total 128 raw suppliers

Chemical Property of CID 657320

Chemical Property:

Appearance/Colour:White to off-white powder
Vapor Pressure:1.47E-13mmHg at 25°C
Melting Point:158-159 °C
Refractive Index:1.63
Boiling Point:395.1 °C at 760 mmHg
Flash Point:192.8 °C
PSA：21.26000
Density:1.254g/cm³
LogP:5.62790
Storage Temp.:Store at RT
Solubility.:H2O: soluble (sparingly)
Water Solubility.:Soluble in dimethylsulfoxide and water.
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:345.1107264
Heavy Atom Count:23
Complexity:308

Purity/Quality:

99.5%min ^*data from raw suppliers

Fluoxetine-d5 Hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn,N
Statements: 22-38-41-50
Safety Statements: 26-36/37/39-61-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:[H+].CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.[Cl-]
Description Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI), it is adapted to the treatment of various depressive disorders, including mild or major depression, bipolar disorder depression, psychogenic depression and depressive neurosis. The mechanism is inhibiting neuronal uptake of serotonin from the synaptic cleft, increasing this neurotransmitter in the gap for practical use , thereby improving the emotional state,and treating depressive disorders. It also appears effective in the treatment of obesity.
Uses Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor. It is used to treat major depressive disorder, bulimia nervosa (an eating disorder) obsessive-compulsive disorder, panic disorder and premenstrual dysphoric disorder (PMDD).
Therapeutic Function Antidepressant

Technology Process of CID 657320

There total 13 articles about CID 657320 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.7%

: 42142-52-9
3-methylamino-1-phenylpropan-1-ol

: 98-56-6
4-chlorobenzotrifluoride

N-methyl-3-[(4-trifluoromethyl)phenoxy]-3-phenyl propylamine hydrochloride (fluoxetine hydrochloride): N-methyl-3-[(4-trifluoromethyl)phenoxy]-3-phenyl propylamine hydrochloride (fluoxetine hydrochloride)

: 56296-78-7
Adofen

Guidance literature:: With hydrogenchloride; potassium hydroxide; In sulfolane; water; toluene;

Reference yield: 95.0%

: N-methyl-N-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)benzamide

: 56296-78-7
Adofen

Guidance literature:: N-methyl-N-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)benzamide; With pyridine hydrogenfluoride; methoxybenzene; at 20 ℃; for 2h; Sealed tube;

With hydrogenchloride; In 1,4-dioxane; tert-butyl methyl ether; water; chemoselective reaction;
DOI:10.1002/anie.201800749