Technology Process of di-tert-butyl (3-amino-5-bromo-4-methylphenyl)carbamate
There total 1 articles about di-tert-butyl (3-amino-5-bromo-4-methylphenyl)carbamate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-bromo-2-methyl-3,5-dinitrobenzene;
With
iron;
In
tetrahydrofuran; ethanol;
at 0 - 80 ℃;
for 2h;
di-tert-butyl dicarbonate;
With
dmap;
In
dichloromethane;
at 20 ℃;
for 3h;
With
palladium on activated charcoal; hydrogen;
In
methanol;
at 20 ℃;
for 4h;
DOI:10.1016/j.bmc.2013.12.033
