C₈H₆ClF₅S

Base Information

• Chemical Name: C₈H₆ClF₅S
• CAS No.: 460745-76-0
• Molecular Formula: C₈H₆ClF₅S
• Molecular Weight: 264.647
• Mol file: 460745-76-0.mol

Synonyms:C₈H₆ClF₅S

Chemical Property of C₈H₆ClF₅S

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₈H₆ClF₅S

There total 2 articles about C₈H₆ClF₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

phenylacetylene (536-74-3) → C8H6ClF5S (460745-76-0)

Guidance literature:

With pentafluorosulfanyl chloride; In diethyl ether; hexane; at -25 ℃; for 6h; Sealed tube; Inert atmosphere; UV-irradiation;

DOI:10.1002/anie.202112575

Reference yield:

phenylacetylene (536-74-3) → C8H6ClF5S (460745-76-0) + C8H6(2)HF5S + C8H6(2)HF5S

Guidance literature:

With pentafluorosulfanyl chloride; 1,1,1,3,3,3-hexamethyl-2-(trimethylsilyl)trisilane-2-d; In diethyl ether; hexane; at -25 ℃; for 6h; Overall yield = 34 percent; diastereoselective reaction; Sealed tube; Inert atmosphere; UV-irradiation;

DOI:10.1002/anie.202112575

Reference yield:

C8H6ClF5S (460745-76-0) → pentafluoro(phenylethynyl)-λ6-sulfane (172166-14-2)

Guidance literature:

With lithium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 2h;

DOI:10.1021/jo9007699

upstream raw materials:

phenylacetylene

Downstream raw materials:

pentafluoro(phenylethynyl)-λ⁶-sulfane

Refernces

• 1、 Birepinte, Mélodie,Champagne, Pier Alexandre,Paquin, Jean-Fran?ois. "Photoinitiated anti-Hydropentafluorosulfanylation of Terminal Alkynes". supporting information. . Retrieved 2021/11/30.