Chloroacetic acid sodium salt

Base Information

• Chemical Name: Chloroacetic acid sodium salt
• CAS No.: 3926-62-3
• Molecular Formula: C2H3ClO2Na
• Molecular Weight: 116.479
• Hs Code.: Oral rat LD50: 95 mg/kg.
• Mol file: 3926-62-3.mol

Synonyms:Aceticacid, chloro-, sodium salt (8CI,9CI);Chloroacetic acid sodium salt;Monochloroacetic acid sodium salt;SMA;SMA (herbicide);Sodium2-chloroacetate;Sodiummonochloroacetate;Sodium a-chloroacetate;

Chemical Property of Chloroacetic acid sodium salt

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 0.259mmHg at 25°C
• Melting Point: 199 °C (dec.)(lit.)
• Refractive Index: FLASH POINT
• Boiling Point: 189 °C at 760 mmHg
• Flash Point: 71.5 °C
• PSA: 40.13000
• Density: 1.399 g/cm3
• LogP: -1.02490
• Storage Temp.: -20°C
• Sensitive.: Hygroscopic
• Solubility.: 820g/l
• Water Solubility.: 440 g/L (20 ºC)

Purity/Quality:

99.9% ^*data from raw suppliers

Sodiumα-Chloroacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T, N
• Hazard Codes: T,N
• Statements: 25-38-50-36
• Safety Statements: 22-37-45-61-26

MSDS Files:

SDS file from LookChem

Useful:

• description: Sodium chloroacetate is a white colored powdered solid. It is soluble in water. It may be toxic ingestion or inhalation. It is used as a contact herbicide and a component in other herbicides, an intermediate in the production of carboxymethyl-cellulose, and other synthetic organic chemicals.In one study systemic effects to Sprague-Dawley rats (M/F, numbers per group not indicated) given single doses of sodium chloroacetate at 94, 282, or 470 mg/kg bw demonstrated increased sodium concentration in urine, increased potassium concentration in plasma, and reduced glutathione level in the liver at the highest dose; 2/3 of males died within 24 hours of treatment in the middle and high dose groups.
• Uses: Sodium chloroacetate is the sodium salt of chloroacetic acid. It is used to prepare weed killers, dyes, vitamins and active pharmaceutical ingredients. It is also used as an odor agent, surface active agent and viscosity adjustor. Sodium dihydroxyethyltallow glycinate is the condensation product of dihydroxyethyl tallow amine and sodiumchloroacetate.It is used as a thickeningagent and asurfactant. Sodium chloroacetate is used to prepare dyes and active pharmaceutical ingredients. It is also used as an odor agent, surface active agent and viscosity adjustor.

Technology Process of Chloroacetic acid sodium salt

There total 4 articles about Chloroacetic acid sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.3%

→ sodium monochloroacetic acid (3926-62-3)

Guidance literature:

Reference yield:

chloroacetic acid (79-11-8) → sodium monochloroacetic acid (3926-62-3)

Guidance literature:

With KB-4P-2(Na); Equilibrium constant; exchange equilibrium constant;

Reference yield:

chloroacetic acid (79-11-8) + sodium hydroxide (1310-73-2) → sodium monochloroacetic acid (3926-62-3)

Guidance literature:

In water;

DOI:10.1039/c5dt01157d

upstream raw materials:

chloroacetic acid

sodium hydroxide

Downstream raw materials:

N-phenylsulfonylglycine

2-[2-oxo-benzo[d]oxazole-3(2H)-yl]acetic acid

2-(benzo[d]oxazol-2-ylthio)acetic acid

2-(dodecylamino)acetic acid

Refernces

• 1、 -. "Synthetic method of 2-methyl-4-chlorophenoxyacetic acid". Paragraph 0018; 0020; 0030; 0031. . Retrieved 2018/03/26.
• 2、 -. "Preparation method for 2,4-dichlorophenoxyacetic acid". Paragraph 0040; 0043; 0046; 0049; 0052; 0053; 0055; 0058. . Retrieved 2018/09/29.