(S)-1-Cbz-3-Aminopyrrolidine hydrochloride

Base Information

Chemical Name:(S)-1-Cbz-3-Aminopyrrolidine hydrochloride
CAS No.:550378-39-7
Molecular Formula:C12H16N2O2^.HCl
Molecular Weight:256.732
Hs Code.:2933990090
Mol file:550378-39-7.mol

Synonyms:1-Pyrrolidinecarboxylicacid, 3-amino-, phenylmethyl ester, monohydrochloride, (3S)- (9CI);(3S)-3-aminopyrrolidine-1-carboxylate de benzyle chlorhydrate;1-Pyrrolidinecarboxylic acid, 3-amino-, phenylmethyl ester, (3S)-, hydrochloride (1:1);benzyl (3S)-3-aminopyrrolidine-1-carboxylate hydrochloride;Benzyl (3S)-3-aminopyrrolidine-1-carboxylate hydrochloride (1:1);Benzyl-(3S)-3-aminopyrrolidin-1-carboxylathydrochlorid;

Suppliers and Price of (S)-1-Cbz-3-Aminopyrrolidine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-1-Cbz-3-AminopyrrolidineHydrochloride
100mg
$ 60.00

TCI Chemical
(S)-3-Amino-1-carbobenzoxypyrrolidine Hydrochloride >98.0%(HPLC)(N)
1g
$ 165.00

TCI Chemical
(S)-3-Amino-1-carbobenzoxypyrrolidine Hydrochloride >98.0%(HPLC)(N)
5g
$ 633.00

Crysdot
(S)-1-Cbz-3-Aminopyrrolidinehydrochloride 97%
10g
$ 356.00

Chem-Impex
(S)-3-Amino-1-carbobenzoxypyrrolidinehydrochloride,98%(Chiralpurity) 98%(Chiralpurity)
1G
$ 164.64

Chem-Impex
(S)-3-Amino-1-carbobenzoxypyrrolidinehydrochloride,98%(Chiralpurity) 98%(Chiralpurity)
5G
$ 622.72

Biosynth Carbosynth
(S)-3-Amino-1-carbobenzoxypyrrolidine Hydrochloride
1 g
$ 90.00

Biosynth Carbosynth
(S)-3-Amino-1-carbobenzoxypyrrolidine Hydrochloride
5 g
$ 314.00

Biosynth Carbosynth
(S)-3-Amino-1-carbobenzoxypyrrolidine Hydrochloride
10 g
$ 534.00

Biosynth Carbosynth
(S)-3-Amino-1-carbobenzoxypyrrolidine Hydrochloride
500 mg
$ 52.00

Total 53 raw suppliers

Chemical Property of (S)-1-Cbz-3-Aminopyrrolidine hydrochloride

Chemical Property:

Vapor Pressure:3.37E-06mmHg at 25°C
Boiling Point:381.7 °C at 760 mmHg
Flash Point:184.6 °C
PSA：55.56000
Density:1.208g/mLat 25°C(lit.)
LogP:2.79640
Storage Temp.:Inert atmosphere,Room Temperature
Water Solubility.:Soluble in water

Purity/Quality:

97% ^*data from raw suppliers

(S)-1-Cbz-3-AminopyrrolidineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-1-Cbz-3-Aminopyrrolidine hydrochloride

There total 2 articles about (S)-1-Cbz-3-Aminopyrrolidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 122536-74-7
(S)-3-<<(1,1-dimethylethoxy)carbonyl>amino>-1-pyrrolidinecarboxylic acid phenylmethyl ester

: 550378-39-7
(S)-benzyl 3-aminopyrrolidine-1-carboxylate hydrochloride

Guidance literature:: With hydrogenchloride; acetic acid; In methoxybenzene; for 0.333333h;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 550378-39-7
(S)-benzyl 3-aminopyrrolidine-1-carboxylate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 0 - 20 °C

2: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C

With hydrogenchloride; triethylamine; In 1,4-dioxane; dichloromethane;
DOI:10.1016/j.bmcl.2011.12.109

Reference yield:

: 550378-39-7
(S)-benzyl 3-aminopyrrolidine-1-carboxylate hydrochloride

: 1253856-46-0
(2S,5S)-5-(4-trifluoromethyl-benzenesulfonyloxy)-piperidine-1,2-dicarboxylic acid 1-tert-butyl ester

: 1253856-48-2
(2S,5S)-2-((S)-1-benzyloxycarbonyl-pyrrolidin-3-ylcarbamoyl)-5-(4-trifluoromethyl-benzenesulfonyloxy)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; 2-hydroxy-pyridine N-oxide; In dichloromethane; at 20 ℃; Inert atmosphere;