Epigallocatechin Gallate

Base Information

Chemical Name:Epigallocatechin Gallate
CAS No.:989-51-5
Deprecated CAS:863-65-0
Molecular Formula:C₂₂H₁₈O₁₁
Molecular Weight:458.378
Hs Code.:29339900
European Community (EC) Number:479-560-7,619-381-5
UNII:BQM438CTEL
DSSTox Substance ID:DTXSID1029889
Nikkaji Number:J134.058A
Wikipedia:Epigallocatechin_gallate
Wikidata:Q393339
NCI Thesaurus Code:C1088
RXCUI:24246
Pharos Ligand ID:8G955XN2LS69
Metabolomics Workbench ID:22118
ChEMBL ID:CHEMBL297453
Mol file:989-51-5.mol

Synonyms:EGCG cpd;epigallo-catechin gallate;epigallocatechin gallate;epigallocatechin-3-gallate;epigallocatechin-3-O-gallate

Suppliers and Price of Epigallocatechin Gallate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
EGCG
50mg
$ 290.00

TRC
(-)-Epigallocatechin gallate
1g
$ 120.00

TRC
(-)-Epigallocatechin gallate
250mg
$ 75.00

Tocris
EGCG ≥98%(HPLC)
50
$ 65.00

TCI Chemical
(-)-Epigallocatechin Gallate Hydrate >98.0%(HPLC)
100mg
$ 118.00

TCI Chemical
(-)-Epigallocatechin Gallate Hydrate >98.0%(HPLC)
500mg
$ 350.00

Sigma-Aldrich
(?)-Epigallocatechin3-gallate phyproof?ReferenceSubstance
50 mg
$ 310.00

Sigma-Aldrich
(?)-Epigallocatechin gallate ≥95%
50mg
$ 300.00

Sigma-Aldrich
(?)-Epigallocatechin gallate United States Pharmacopeia (USP) Reference Standard
20mg
$ 325.00

Sigma-Aldrich
(?)-Epigallocatechin gallate analytical standard
10mg
$ 273.00

Total 243 raw suppliers

Chemical Property of Epigallocatechin Gallate

Chemical Property:

Appearance/Colour:Solid
Vapor Pressure:3.71E-35mmHg at 25°C
Melting Point:222-224 °C
Refractive Index:-175.5 ° (C=1, EtOH)
Boiling Point:909.1 °C at 760 mmHg
PKA:7.75±0.25(Predicted)
Flash Point:320 °C
PSA：197.37000
Density:1.9 g/cm³
LogP:2.23320
Storage Temp.:2-8°C
Solubility.:H2O: ≥5mg/mL, clear
Water Solubility.:Soluble in ethanol, dimethyl formamide, water.
XLogP3:1.2
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:4
Exact Mass:458.08491139
Heavy Atom Count:33
Complexity:667

Purity/Quality:

99% ^*data from raw suppliers

EGCG ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:

Useful:

Canonical SMILES:C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Isomeric SMILES:C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Recent ClinicalTrials:Oxygen Atomizing Inhalation of EGCG in the Treatment Interstitial Pneumonia in Cancer Patients
Recent EU Clinical Trials:Topical sinecatechins ointment in treatment of primary superficial Basal Cell Carcinoma: a double blind, randomized, placebo-controlled trial.
Uses (-)-Epigallocatechin Gallate is a tumor-inhibiting constituent of green tea. (-)-Epigallocatechin Gallate alters the cleavage of amyloid precursor protein, decreasing production of amaloid-? and amaloid plaques in mice. (-)-Epigallocatechin gallate has neuroprotective properties. telomerase inhibitor An inhibitor of Bcl-2 and NOS2 (-)-Epigallocatechin Gallate is a tumor-inhibiting constituent of green tea. (-)-Epigallocatechin Gallate alters the cleavage of amyloid precursor protein, decreasing production of amaloid-β and amaloid plaques in mice. (-)-Epigallocatechin gallate has neuroprotective properties. A tumor-inhibiting constituent of green tea. Alters the cleavage of amyloid precursor protein, decreasing production of amaloid- and amaloid plaques in mice

Technology Process of Epigallocatechin Gallate

There total 49 articles about Epigallocatechin Gallate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.6%