Technology Process of 1-amino-N-(2,4-dimethoxybenzyl)-3-methyl-1H-pyrrole-2-carboxamide
There total 5 articles about 1-amino-N-(2,4-dimethoxybenzyl)-3-methyl-1H-pyrrole-2-carboxamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium hydroxide; sodium hypochlorite; Aliquat 336; ammonium chloride; sodium hydroxide;
In
diethyl ether; tert-butyl methyl ether; water;
at 0 - 20 ℃;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Cooling with ice
2: sodium hydroxide; ammonium hydroxide; ammonium chloride; sodium hypochlorite; Aliquat 336 / diethyl ether; water; tert-butyl methyl ether / 0 - 20 °C
With
ammonium hydroxide; sodium hypochlorite; Aliquat 336; ammonium chloride; N-ethyl-N,N-diisopropylamine; sodium hydroxide;
In
diethyl ether; dichloromethane; tert-butyl methyl ether; water;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydroxide / water; methanol / 60 °C
2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 3 h / 20 °C
3: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Cooling with ice
4: sodium hydroxide; ammonium hydroxide; ammonium chloride; sodium hypochlorite; Aliquat 336 / diethyl ether; water; tert-butyl methyl ether / 0 - 20 °C
With
ammonium hydroxide; sodium hypochlorite; oxalyl dichloride; Aliquat 336; ammonium chloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; sodium hydroxide;
In
methanol; diethyl ether; dichloromethane; tert-butyl methyl ether; water;
