methyl N-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}glycinate

Base Information

Chemical Name:methyl N-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}glycinate
CAS No.:881314-46-1
Molecular Formula:C₂₇H₂₅FN₂O₃
Molecular Weight:444.506
Hs Code.:

Synonyms:methyl N-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}glycinate

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Chemical Property of methyl N-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}glycinate

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Technology Process of methyl N-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}glycinate

There total 1 articles about methyl N-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

: 881314-44-9
methyl N-{[2-(4-bromophenyl)-6-fluoroquinolin-4-yl]methyl}glycinate

: 213211-69-9
(2-ethoxyphenyl)boronic acid

: 881314-46-1
methyl N-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}glycinate

Guidance literature:: With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,2-dimethoxyethane; water; at 50 ℃; for 16h;

Reference yield: 31.0%

: 881314-46-1
methyl N-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}glycinate

: 881314-50-7
N-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}glycine

Guidance literature:: methyl N-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}glycinate; With lithium hydroxide; water; In tetrahydrofuran; at 50 ℃; for 6h;

With hydrogenchloride; In tetrahydrofuran; water; pH=6;