tert-butyl ((2S,3R)-3-hydroxy-4-(N-pentylbenzo[d]thiazole-6-sulfonamido)-1-phenylbutan-2-yl)carbamate

Base Information

• Chemical Name: tert-butyl ((2S,3R)-3-hydroxy-4-(N-pentylbenzo[d]thiazole-6-sulfonamido)-1-phenylbutan-2-yl)carbamate
• CAS No.: 1026701-58-5
• Molecular Formula: C₂₇H₃₇N₃O₅S₂
• Molecular Weight: 547.74
• Mol file: 1026701-58-5.mol

Synonyms:tert-butyl ((2S,3R)-3-hydroxy-4-(N-pentylbenzo[d]thiazole-6-sulfonamido)-1-phenylbutan-2-yl)carbamate

Chemical Property of tert-butyl ((2S,3R)-3-hydroxy-4-(N-pentylbenzo[d]thiazole-6-sulfonamido)-1-phenylbutan-2-yl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl ((2S,3R)-3-hydroxy-4-(N-pentylbenzo[d]thiazole-6-sulfonamido)-1-phenylbutan-2-yl)carbamate

There total 2 articles about tert-butyl ((2S,3R)-3-hydroxy-4-(N-pentylbenzo[d]thiazole-6-sulfonamido)-1-phenylbutan-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1-oxiranyl-2-phenylethyl)carbamic acid tert-butyl ester (98760-08-8,98818-34-9,98818-35-0,103127-56-6,98737-29-2) → tert-butyl ((2S,3R)-3-hydroxy-4-(N-pentylbenzo[d]thiazole-6-sulfonamido)-1-phenylbutan-2-yl)carbamate (1026701-58-5)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol

2: triethylamine / dichloromethane / 5 h / 0 - 20 °C

With triethylamine; In ethanol; dichloromethane;

DOI:10.1021/jm300238h

Reference yield:

n-Pentylamine (110-58-7) → tert-butyl ((2S,3R)-3-hydroxy-4-(N-pentylbenzo[d]thiazole-6-sulfonamido)-1-phenylbutan-2-yl)carbamate (1026701-58-5)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol

2: triethylamine / dichloromethane / 5 h / 0 - 20 °C

With triethylamine; In ethanol; dichloromethane;

DOI:10.1021/jm300238h

Reference yield:

tert-butyl ((2S,3R)-3-hydroxy-4-(N-pentylbenzo[d]thiazole-6-sulfonamido)-1-phenylbutan-2-yl)carbamate (1026701-58-5) → C22H29N3O3S2 (1026701-96-1)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/ja076558p

upstream raw materials:

(1-oxiranyl-2-phenylethyl)carbamic acid tert-butyl ester

n-Pentylamine

Downstream raw materials:

C₂₂H₂₉N₃O₃S₂

C₂₈H₃₇N₃O₇S₂

C₂₇H₃₃F₃N₄O₆S₂

C₂₇H₃₄Cl₂N₄O₆S₂