N'-(2-fluoro-5-(trifluoromethyl)phenyl)-N-phenylacetimidamide

Base Information

• Chemical Name: N'-(2-fluoro-5-(trifluoromethyl)phenyl)-N-phenylacetimidamide
• CAS No.: 1519051-05-8
• Molecular Formula: C₁₅H₁₂F₄N₂
• Molecular Weight: 296.267
• Mol file: 1519051-05-8.mol

Synonyms:N'-(2-fluoro-5-(trifluoromethyl)phenyl)-N-phenylacetimidamide

Chemical Property of N'-(2-fluoro-5-(trifluoromethyl)phenyl)-N-phenylacetimidamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N'-(2-fluoro-5-(trifluoromethyl)phenyl)-N-phenylacetimidamide

There total 1 articles about N'-(2-fluoro-5-(trifluoromethyl)phenyl)-N-phenylacetimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N-(2-fluoro-5-(trifluoromethyl)phenyl)acetamide (349-27-9) + aniline (62-53-3) → N'-(2-fluoro-5-(trifluoromethyl)phenyl)-N-phenylacetimidamide (1519051-05-8)

Guidance literature:

N-(2-fluoro-5-(trifluoromethyl)phenyl)acetamide; With 2,6-dimethylpyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;

aniline; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol403414v

Reference yield: 79.0%

N'-(2-fluoro-5-(trifluoromethyl)phenyl)-N-phenylacetimidamide (1519051-05-8) → 2-methyl-1-phenyl-5-(trifluoromethyl)-1H-benzo[d]imidazole (1427-14-1)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 120 ℃; for 16h; Inert atmosphere; Sealed tube;

DOI:10.1021/ol403414v

upstream raw materials:

N-(2-fluoro-5-(trifluoromethyl)phenyl)acetamide

aniline

Downstream raw materials:

2-methyl-1-phenyl-5-(trifluoromethyl)-1H-benzo[d]imidazole