Boc-L-aspartic acid 1-benzyl ester

Base Information

Chemical Name:Boc-L-aspartic acid 1-benzyl ester
CAS No.:30925-18-9
Molecular Formula:C16H21NO6
Molecular Weight:323.346
Hs Code.:29242990
European Community (EC) Number:685-355-5
DSSTox Substance ID:DTXSID90426912
Nikkaji Number:J934.891C
Wikidata:Q72448539
Mol file:30925-18-9.mol

Synonyms:Boc-Asp-OBzl;t-butyloxycarbonylaspartic acid alpha-benzyl ester

Suppliers and Price of Boc-L-aspartic acid 1-benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-tert-Butoxycarbonyl-L-aspartic Acid α-Benzyl Ester
1g
$ 305.00

TRC
N-tert-Butoxycarbonyl-L-asparticAcidα-BenzylEster
25g
$ 130.00

TCI Chemical
1-Benzyl N-(tert-Butoxycarbonyl)-L-aspartate >98.0%(HPLC)(T)
25g
$ 146.00

TCI Chemical
1-Benzyl N-(tert-Butoxycarbonyl)-L-aspartate >98.0%(HPLC)(T)
5g
$ 38.00

Sigma-Aldrich
Boc-Asp-OBzl ≥98.0% (TLC)
5g
$ 72.90

Sigma-Aldrich
Boc-Asp-OBzl Novabiochem?
25 g
$ 242.00

Sigma-Aldrich
Boc-Asp-OBzl Novabiochem . CAS 30925-18-9, molar mass 323.34 g/mol., Novabiochem
8530140025
$ 234.00

Sigma-Aldrich
Boc-Asp-OBzl ≥98.0% (TLC)
25g
$ 197.00

Iris Biotech GmbH
Boc-L-Asp-OBzl
100 g
$ 506.25

Iris Biotech GmbH
Boc-L-Asp-OBzl
25 g
$ 202.50

Total 106 raw suppliers

Chemical Property of Boc-L-aspartic acid 1-benzyl ester

Chemical Property:

Vapor Pressure:5.43E-11mmHg at 25°C
Melting Point:95-97 °C
Refractive Index:-22.6 ° (C=1, MeOH)
Boiling Point:504.3 °C at 760 mmHg
PKA:4.09±0.19(Predicted)
Flash Point:258.8 °C
PSA：101.93000
Density:1.219 g/cm³
LogP:2.48870
Storage Temp.:Store at 0°C
Solubility.:Soluble in dichloromethane
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:323.13688739
Heavy Atom Count:23
Complexity:423

Purity/Quality:

99% ^*data from raw suppliers

N-tert-Butoxycarbonyl-L-aspartic Acid α-Benzyl Ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC(=O)O)C(=O)OCC1=CC=CC=C1
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC(=O)O)C(=O)OCC1=CC=CC=C1
Uses N-Boc-L-aspartic acid 1-benzyl ester is used as a local anesthetic and also used in agrochemical, pharmaceutical and dyestuff field.

Technology Process of Boc-L-aspartic acid 1-benzyl ester

There total 5 articles about Boc-L-aspartic acid 1-benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 13726-67-5
Boc-Asp-OH

: 100-51-6,185532-71-2
benzyl alcohol

: 30925-18-9
2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester

Guidance literature:: With ethylenediaminetetraacetic acid; rac-cysteine; papain; In dichloromethane; at 37 ℃; for 8h;
DOI:10.1016/S0040-4020(01)81493-9

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 104-15-4
toluene-4-sulfonic acid

: 617-45-8,25608-40-6,27881-03-4,32505-46-7,52526-39-3
aspartic Acid

: 100-51-6,185532-71-2
benzyl alcohol

: 30925-18-9
2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester

Guidance literature:: toluene-4-sulfonic acid; aspartic Acid; benzyl alcohol; In benzene; Heating;

With hydrogen bromide; acetic acid;

di-tert-butyl dicarbonate; With sodium carbonate; In water; isopropyl alcohol; at 0 ℃; Further stages.;
DOI:10.1039/b104137c