Azacyclonol

Base Information

Chemical Name:Azacyclonol
CAS No.:115-46-8
Molecular Formula:C18H21NO
Molecular Weight:267.371
Hs Code.:29333999
European Community (EC) Number:204-092-5
UNII:2MMR990PEM
DSSTox Substance ID:DTXSID2045280
Nikkaji Number:J5.268J
Wikipedia:Azacyclonol
Wikidata:Q4832014
NCI Thesaurus Code:C76502
ChEMBL ID:CHEMBL127508
Mol file:115-46-8.mol

Synonyms:azacyclonol;azacyclonol hydrochloride

Suppliers and Price of Azacyclonol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α-(4-Piperidyl)benzhydrol
100g
$ 410.00

TRC
α-(4-Piperidyl)benzhydrol
50mg
$ 65.00

TCI Chemical
α-(4-Piperidyl)benzhydrol >99.0%(GC)(T)
5g
$ 36.00

TCI Chemical
α-(4-Piperidyl)benzhydrol >99.0%(GC)(T)
25g
$ 116.00

Sigma-Aldrich
Diphenyl-4-piperidinemethanol for synthesis. CAS 115-46-8, EC Number 204-092-5, molar mass 267.37 g/mol., for synthesis
8149730025
$ 92.40

Sigma-Aldrich
Diphenyl-4-piperidinemethanol for synthesis
25 g
$ 88.52

Oakwood
Diphenyl-piperidin-4-yl-methanol 99%
1g
$ 10.00

Medical Isotopes, Inc.
α-(4-Piperidyl)benzhydrol
25 g
$ 605.00

Medical Isotopes, Inc.
α-(4-Piperidyl)benzhydrol
100 mg
$ 575.00

Medical Isotopes, Inc.
α-(4-Piperidyl)benzhydrol
100 g
$ 845.00

Total 181 raw suppliers

Chemical Property of Azacyclonol

Chemical Property:

Appearance/Colour:white to light beige crystalline powder
Vapor Pressure:1.02E-08mmHg at 25°C
Melting Point:160-163 °C
Refractive Index:1.584
Boiling Point:445.5 °C at 760 mmHg
PKA:13.32±0.29(Predicted)
Flash Point:142 °C
PSA：32.26000
Density:1.103 g/cm³
LogP:3.25090
Storage Temp.:Store below +30°C.
Solubility.:Chloroform, Methanol (Slightly, Sonicated)
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:267.162314293
Heavy Atom Count:20
Complexity:268

Purity/Quality:

99% ^*data from raw suppliers

α-(4-Piperidyl)benzhydrol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1C(C2=CC=CC=C2)(C3=CC=CC=C3)O
Uses α-(4-Piperidyl)benzhydrol is a key intermediate in the synthesis of Fexofenadine (F322490). Fexofenadine EP Impurity E. Anxiolytic;H1 antagonist α-(4-Piperidyl)benzhydrol is a key intermediate in the synthesis of Fexofenadine (F322490).
Therapeutic Function Tranquilizer

Technology Process of Azacyclonol

There total 25 articles about Azacyclonol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 114399-88-1
α,α-diphenyl-1-(phenylmethyl)-4-piperidinemethanol

: 115-46-8
C₁₈H₂₁NO

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 70 ℃; under 2585.7 Torr;
DOI:10.1021/jm00121a022

Reference yield: 95.0%

: (1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)diphenylmethanol

: 115-46-8
C₁₈H₂₁NO

Guidance literature:: With hydrogen; palladium(II) hydroxide; In methanol; at 10 - 20 ℃; for 5h; under 258.581 Torr; Reagent/catalyst; Autoclave;