(4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)methyloctanoylamide

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Chemical Name:(4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)methyloctanoylamide
CAS No.:817618-03-4
Molecular Formula:C₃₅H₄₄N₂O₅S
Molecular Weight:604.811
Hs Code.:

Synonyms:(4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)methyloctanoylamide

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Chemical Property of (4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)methyloctanoylamide

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Technology Process of (4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)methyloctanoylamide

There total 1 articles about (4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)methyloctanoylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 817618-02-3
N-(4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-1(S)-hydroxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)-N-methyloctanoylamide

: 817618-03-4
(4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)methyloctanoylamide

Guidance literature:: N-(4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-1(S)-hydroxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)-N-methyloctanoylamide; With sodium hexamethyldisilazane; In dichloromethane; at -78 ℃; for 1h;

With phenylcarbonochloridothioate; In dichloromethane; at -78 - 20 ℃; for 3h;

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 110 ℃; for 0.5h;

Reference yield: 76.0%

: 817618-03-4
(4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)methyloctanoylamide

: 2(S)-ethoxy-3-(4-{5-[(methyloctanoylamino)methyl]thiophen-3-yl}phenyl)propanoic acid

Guidance literature:: (4-{4-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]phenyl}thiophen-2-ylmethyl)methyloctanoylamide; With lithium hydroxide; water; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

With sodium hydroxide; In tetrahydrofuran; ethyl acetate; pH=8 - 9;

With hydrogenchloride; In water; pH=3 - 4;