N^α-t-butoxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanyl-N^ω-nitro-L-arginyl-L-isoleucine 4-picolyl ester

Base Information

• Chemical Name: N^α-t-butoxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanyl-N^ω-nitro-L-arginyl-L-isoleucine 4-picolyl ester
• CAS No.: 83030-69-7
• Molecular Formula: C₇₄H₁₀₁N₁₉O₁₈
• Molecular Weight: 1544.73

Synonyms:N^α-t-butoxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanyl-N^ω-nitro-L-arginyl-L-isoleucine 4-picolyl ester

Chemical Property of N^α-t-butoxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanyl-N^ω-nitro-L-arginyl-L-isoleucine 4-picolyl ester

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Technology Process of N^α-t-butoxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanyl-N^ω-nitro-L-arginyl-L-isoleucine 4-picolyl ester

There total 2 articles about N^α-t-butoxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanyl-N^ω-nitro-L-arginyl-L-isoleucine 4-picolyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

Nα-t-butoxycarbonyl-Nω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanine (83030-60-8) + Nω-nitro-L-arginyl-isoleucine 4-picolyl ester (83030-66-4) → Nα-t-butoxycarbonyl-Nω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanyl-Nω-nitro-L-arginyl-L-isoleucine 4-picolyl ester (83030-69-7)

Guidance literature:

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 0 ℃;

Reference yield:

C56H73N15O13 + Nω-nitro-L-arginyl-isoleucine 4-picolyl ester (83030-66-4) → Nα-t-butoxycarbonyl-Nω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanyl-Nω-nitro-L-arginyl-L-isoleucine 4-picolyl ester (83030-69-7)

Guidance literature:

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 0 ℃; for 18h; Yield given;

upstream raw materials:

N^α-t-butoxycarbonyl-N^ω-nitro-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-O-benzyl-L-seryl-L-prolyl-L-phenylalanine

N^ω-nitro-L-arginyl-isoleucine 4-picolyl ester

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