2-tert-butoxy-5-(tert-butyl-dimethyl-silanoxy)-1-methyl-cyclohexane-1,4-dicarboxylic acid

Base Information

• Chemical Name: 2-tert-butoxy-5-(tert-butyl-dimethyl-silanoxy)-1-methyl-cyclohexane-1,4-dicarboxylic acid
• CAS No.: 952717-64-5
• Molecular Formula: C₁₉H₃₆O₆Si
• Molecular Weight: 388.577
• Mol file: 952717-64-5.mol

Synonyms:2-tert-butoxy-5-(tert-butyl-dimethyl-silanoxy)-1-methyl-cyclohexane-1,4-dicarboxylic acid

Chemical Property of 2-tert-butoxy-5-(tert-butyl-dimethyl-silanoxy)-1-methyl-cyclohexane-1,4-dicarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-tert-butoxy-5-(tert-butyl-dimethyl-silanoxy)-1-methyl-cyclohexane-1,4-dicarboxylic acid

There total 2 articles about 2-tert-butoxy-5-(tert-butyl-dimethyl-silanoxy)-1-methyl-cyclohexane-1,4-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

5-tert-butoxy-7-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-4-methyl-bicyclo[2.2.2]octan-2-one (929097-27-8) → 5-tert-butoxy-2-(tert-butyl-dimethyl-silanyloxy)-4-formyl-4-methyl-cyclohexane carboxylic acid (929097-51-8) + 2-tert-butoxy-5-(tert-butyl-dimethyl-silanoxy)-1-methyl-cyclohexane-1,4-dicarboxylic acid (952717-64-5)

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 25 ℃; for 1.5h;

DOI:10.1002/ejoc.200700321

Reference yield: 45.0%

5-tert-butoxy-7-(tert-butyl-dimethyl-silanyloxy)-4-methyl-3-(trimethyl-silanyloxy)-bicyclo[2.2.2]octan-2-one (929097-32-5) → 5-tert-butoxy-2-(tert-butyl-dimethyl-silanyloxy)-4-formyl-4-methyl-cyclohexane carboxylic acid (929097-51-8) + 2-tert-butoxy-5-(tert-butyl-dimethyl-silanoxy)-1-methyl-cyclohexane-1,4-dicarboxylic acid (952717-64-5) + 6-tert-butoxy-8-(tert-butyl-dimethyl-silanyloxy)-5-methyl-4-(trimethyl-silanyloxy)-3-oxa-bicyclo[2.2.2]nonan-2-one

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 25 ℃; for 22h;

DOI:10.1002/ejoc.200700321

Reference yield: 88.0%

2-tert-butoxy-5-(tert-butyl-dimethyl-silanoxy)-1-methyl-cyclohexane-1,4-dicarboxylic acid (952717-64-5) + diazomethyl-trimethyl-silane (18107-18-1) → 2-tert-butoxy-5-(tert-butyl-dimethyl-silanoxy)-1-methyl-cyclohexane-1,4-dicarboxylic acid dimethyl ester

Guidance literature:

In methanol; diethyl ether; for 0.25h;

DOI:10.1002/ejoc.200700321

upstream raw materials:

5-tert-butoxy-7-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-4-methyl-bicyclo[2.2.2]octan-2-one

5-tert-butoxy-7-(tert-butyl-dimethyl-silanyloxy)-4-methyl-3-(trimethyl-silanyloxy)-bicyclo[2.2.2]octan-2-one