N-[7-(4-cyclobutylthiazol-2-yl)naphthalen-2-yl]-2-cyclohexylsuccinamic acid

Base Information

Chemical Name:N-[7-(4-cyclobutylthiazol-2-yl)naphthalen-2-yl]-2-cyclohexylsuccinamic acid
CAS No.:1613317-08-0
Molecular Formula:C₂₇H₃₀N₂O₃S
Molecular Weight:462.613
Hs Code.:

Synonyms:N-[7-(4-cyclobutylthiazol-2-yl)naphthalen-2-yl]-2-cyclohexylsuccinamic acid

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Chemical Property of N-[7-(4-cyclobutylthiazol-2-yl)naphthalen-2-yl]-2-cyclohexylsuccinamic acid

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Technology Process of N-[7-(4-cyclobutylthiazol-2-yl)naphthalen-2-yl]-2-cyclohexylsuccinamic acid

There total 2 articles about N-[7-(4-cyclobutylthiazol-2-yl)naphthalen-2-yl]-2-cyclohexylsuccinamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1613317-26-2
7-(4-cyclobutylthiazol-2-yl)naphthalen-2-ylamine

: 5962-96-9
2-Cyclohexylbutandisaeure-anhydrid

: 1613317-08-0
N-[7-(4-cyclobutylthiazol-2-yl)naphthalen-2-yl]-2-cyclohexylsuccinamic acid

Guidance literature:: In chloroform; at 65 ℃; for 0.5h; Inert atmosphere;

Reference yield:

: 2-(7-bromonaphthalen-2-yl)-4-cyclobutylthiazole

: 1613317-08-0
N-[7-(4-cyclobutylthiazol-2-yl)naphthalen-2-yl]-2-cyclohexylsuccinamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: benzophenoneimine; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; sodium t-butanolate / toluene / 90 °C / Inert atmosphere

2: chloroform / 0.5 h / 65 °C / Inert atmosphere

With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; benzophenoneimine; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; sodium t-butanolate; In chloroform; toluene;