Cefepime hydrochloride

Base Information

• Chemical Name: Cefepime hydrochloride
• CAS No.: 123171-59-5
• Molecular Formula: C19H25ClN6O5S2^.HCl^.H2O
• Molecular Weight: 571.49
• Hs Code.: 29419000
• European Community (EC) Number: 642-959-3
• Mol file: 123171-59-5.mol

Synonyms:Pyrrolidinium,1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-,chloride, monohydrochloride, monohydrate (9CI);Pyrrolidinium,1-[[7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-,chloride, monohydrochloride, monohydrate, [6R-[6a,7b(Z)]]-;Cefepime dihydrochloride monohydrate;Cefepime 2HCl;

Chemical Property of Cefepime hydrochloride

Chemical Property:

• Appearance/Colour: White to pale yellow powder
• Melting Point: 150°C (dec.)
• PSA: 212.81000
• LogP: 1.12860
• Storage Temp.: Store at 0-5°C
• Sensitive.: Light Sensitive
• Solubility.: Soluble in DMSO
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 6
• Exact Mass: 516.1016380
• Heavy Atom Count: 33
• Complexity: 869

Purity/Quality:

99.9% ^*data from raw suppliers

Cefepime dihydrochloride monohydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38-42/43
• Safety Statements: 22-26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[N+]1(CCCC1)CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)[O-].Cl
• Recent EU Clinical Trials: A Phase 3, Multi-Center, Randomized, Single-Blind Study to Assess the Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy in Adults With Complicated Urinary Tract Infection, Acute Uncomplicated Pyelonephritis, Hospital-Acquired Bacterial Pneumonia, Ventilator-Associated Bacterial Pneumonia, and Complicated Intra-Abdominal Infection due to Carbapenem-Resistant Enterobacterales
• Uses: antipsoriatic, protein synthesis inhibitor Semisynthetic, fourth generation cephalosporin antibiotic. Antibacterial Cefepime hydrochloride monohydrate is used as a broad spectrum antibiotic targeting a wide variety of naturally antibiotic resistant Gram-positive and Gram-negative bacteria. It is resistant to hydrolysis by common plasmid and/or chromosomally-mediated β-lactamases.